Van Tyne D, Gilmore M. A delicate balance: maintaining mutualism to prevent disease.. Cell Host Microbe. 2014;16(4):425–7.
Abstract
The intestinal microbial ecosystem is complex, and few of the principles that contribute to homeostasis in health are well understood. Pham et al. (2014) show that a network including the epithelial interleukin-22 receptor protects against infection with the opportunistic pathogen Enterococcus faecalis through promotion of host-microbiota mutualism.