Leangelo was born and raised in Miami, Florida in a Jamaican immigrant family. He attended Princeton University where he majored in Ecology and Evolutionary Biology. During his undergraduate career, volunteered as an emergency medical technician with the Princeton First Aid and Rescue Squad in Princeton, NJ. He also volunteered with the Petey Greene Prisoner Tutoring Program in Chesterfield, NJ, where he taught mathematics to prisoners in maximum security at A.C. Wagner Youth Correctional Facility to help them receive their high diplomas and GED. From 2012 to 2014, he worked as a case manager at the Crisis Ministry in Trenton and Princeton, NJ, where helped low-income tenants facing threats of homelessness, such as eviction, to obtain financial assistance for housing and assisted families to apply for food stamps and to choose from the free food pantry. In the summer of 2013, he completed his senior thesis research in Laikipia, Kenya, where he examined the relationships between water, sanitation, seasonal drivers, and diarrheal diseases.

After graduating in 2014, Leangelo worked as an HIV tester and counselor at the Emergency Department of Thomas Jefferson University Hospital in Philadelphia, PA. With a CDC grant, he pioneered an opt-out routine HIV testing project in which he trained health staff to perform HIV testing and counseling. In addition to performing HIV testing himself, he counseled a diversity of patients about risk reduction and prevention of STIs. In addition, he linked patients who were newly diagnosed with HIV to medical care management and HIV resources.

Now Leangelo is a Pathways M1 MD student at Harvard Medical School. His academic interests include public heath and infectious disease. On campus, Leangelo serves as the Parliamentarian and Community Outreach Liaison of the Student National Medical Association. His main duties include maintaining order at the executive board meetings and organizing community outreach activities for medical students to engage in the surrounding neighborhoods. Outside of school, Leangelo enjoys playing tennis and volleyball, as well as traveling.