vkarimni@bidmc.harvard.edu
Thu, 27 Mar 2025 22:50:19 +0000

BIDMC Detection Unit Enables Breakthrough in Anti-Aging Liver Therapy vkarimni@bidmc… Thu, 03/27/2025 - 18:50

A recent Aging Cell publication by Drs. Alice Rodrigues, Jan Heng, and Frank Slack identified miR-30c-5p, found in extracellular vesicles from young mice, as a promising therapeutic for reversing age-related liver fibrosis. The treatment improved insulin sensitivity and extended health span—offering new potential for regenerative medicine.

Detection Unit Technology That Made It Possible

This discovery was made possible by the Detection Unit of the Precision RNA Medicine Core, which performed high-throughput miRNA screening using Mirxes qPCR technology—capable of quantifying up to 372 miRNAs per sample with high sensitivity. The team also supported downstream data analysis to pinpoint candidates with therapeutic potential.

If you're working on any project requiring sensitive RNA detection and profiling—this is the core that enables it.

Read the full study

Thursday, March 27, 2025, 12:00pm