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Positions We will have open positions in 2022 for postdocs and students with very strong computational and/or mathematical background, especially those with C/C++ programming experience or previous research experience in statistical genetics. Please send your CV and a brief statement of your...

HI-CNV The HI-CNV software ( Hujoel et al. 2022 Cell) calls copy-number variants (CNVs) from SNP-array genotyping probe intensity data in large cohorts. HI-CNV uses a haplotype-informed approach that improves power to detect shorter CNVs (spanning as few as two genotyping probes) by incorporating...

Sebastian Marquardt, PhD Mary Couvillion, PhD Jordi Xiol, PhD Andreas Mayer, PhD Xing Liu, PhD Stephen M Doris, PhD Daniel Holoch, PhD Anthony C. Chiu, PhD Florian Lienert, PhD Linfeng Huang, PhD Magdalena Murawska, PhD Clarissa Scholes, PhD Dane Hazelbaker, Phd Yuliya Sytnikova, PhD Adnan Syed, PhD

Goal: To prepare glycoproteins for N-glycan isolation and analysis by mass spectrometry. Notes: Glassware and glass tubes are cleaned with MilliQ water and dried beforehand. Reagents are weighted on aluminum foil with utensils cleaned with MilliQ water beforehand. Whenever possible, liquid reagents...

Neha Deshpande, MS Research Assistant neha_deshpande@MEEI.HARVARD.EDU Laboratory management Mechanisms elucidating the role of oxidative stress in Fuchs Endothelial Corneal Dystrophy Cailing Liu, PhD Research Associate Cailing_liu@meei.harvard.edu Roles of DJ-1 and Nrf2 in the development of Fuchs...

1. Introduction: 1.1.Primary objective is to determine the binding specificity of a Monoclonal Antibody submitted by investigators, using the printed glycan microarray. 2. Reference: 2.1. www.functionalglycomics.org 3. Materials needed: 3.1.Glycan printed slides , printed on the side of the slide...