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Diagnostics

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Underlying application of new antimicrobial therapeutics is the need to rapidly identify organisms and determine which antimicrobials therapies will be effective. Therefore, the Laboratory is also actively involved in several projects to refine and improve clinical diagnostics: 1) The Antimicrobial...

Image analysis and artificial intelligence in infectious disease diagnostics.

Publication: Journal Article

Smith, K P, and J E Kirby. 2020. “Image Analysis and Artificial Intelligence in Infectious Disease Diagnostics.”. Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 26 (10): 1318-23.

Rapid Susceptibility Testing Methods.

Publication: Journal Article

Smith, Kenneth P, and James E Kirby. 2019. “Rapid Susceptibility Testing Methods.”. Clinics in Laboratory Medicine 39 (3): 333-44.

Synergistic Combinations and Repurposed Antibiotics Active against the Pandrug-Resistant Klebsiella pneumoniae Nevada Strain.

Publication: Journal Article

Brennan-Krohn, Thea, and James E Kirby. 2019. “Synergistic Combinations and Repurposed Antibiotics Active Against the Pandrug-Resistant Klebsiella Pneumoniae Nevada Strain.”. Antimicrobial Agents and Chemotherapy 63 (9).

When One Drug Is Not Enough: Context, Methodology, and Future Prospects in Antibacterial Synergy Testing.

Publication: Journal Article

Brennan-Krohn, Thea, and James E Kirby. 2019. “When One Drug Is Not Enough: Context, Methodology, and Future Prospects in Antibacterial Synergy Testing.”. Clinics in Laboratory Medicine 39 (3): 345-58.

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method.

Publication: Journal Article

Brennan-Krohn, Thea, and James E Kirby. 2019. “Antimicrobial Synergy Testing by the Inkjet Printer-Assisted Automated Checkerboard Array and the Manual Time-Kill Method.”. Journal of Visualized Experiments : JoVE, no. 146.

The Inoculum Effect in the Era of Multidrug Resistance: Minor Differences in Inoculum Have Dramatic Effect on MIC Determination.

Publication: Journal Article

Smith, Kenneth P, and James E Kirby. 2018. “The Inoculum Effect in the Era of Multidrug Resistance: Minor Differences in Inoculum Have Dramatic Effect on MIC Determination.”. Antimicrobial Agents and Chemotherapy 62 (8).

Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline.

Publication: Journal Article

Chen, Alice, Kenneth P Smith, Betsy A Whitfield, Paola C Zucchi, Todd M Lasco, Tiffany E Bias, James E Kirby, and Elizabeth B Hirsch. 2017. “Activity of Minocycline Against Klebsiella Pneumoniae Carbapenemase (KPC)-Producing Enterobacteriaceae Clinical Isolates, With Comparison to Doxycycline and Tigecycline.”. Diagnostic Microbiology and Infectious Disease 88 (4): 365-67.

Verification of an Automated, Digital Dispensing Platform for At-Will Broth Microdilution-Based Antimicrobial Susceptibility Testing.

Publication: Journal Article

Smith, Kenneth P, and James E Kirby. 2016. “Verification of an Automated, Digital Dispensing Platform for At-Will Broth Microdilution-Based Antimicrobial Susceptibility Testing.”. Journal of Clinical Microbiology 54 (9): 2288-93.

2024-2025 Grand Rounds Schedule

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Date Speaker & Topic 9/20/2024 Sarah E. Schroeppel DeBacker, MD, RPVI, DAVBLM The Ethics of AI in Radiology 9/27/2024 Drs. Andrew Beauchesne, Nicholas Spittler, Jessica Shi Department of Radiology Chief Rounds 10/4/2024 Lori Strachowski, MD O-RADS Assessment of Adnexal Lesions: Why, When and How (To...