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AgRP neuron cis-regulatory analysis across hunger states reveals that IRF3 mediates leptin's acute effects

Publication: Journal Article

Heyward, Frankie D., Nan Liu, Christopher L Jacobs, Natalia L.S. Machado, Rachael Ivison, Aykut Uner, Harini Srinivasan, et al. 2024. “AgRP Neuron Cis-Regulatory Analysis across Hunger States Reveals That IRF3 Mediates Leptin’s Acute Effects”. Nature Communication 15 (1): 4646.

The BIDMC Institute of Gut-Brain Research at Digestive Disease Week 2025!

News: May 06, 2025

IGBR had a fantastic experience attending the 2025 annual Digestive Disease Week (DDW) in San Diego, CA! Our team was excited to present the latest research on neurogastrointestinal disorders and contribute to important conversations surrounding clinical care. See below for a few highlights from the...

A hypothalamic circuit for circadian regulation of corticosterone secretion

Publication: Journal Article

Ramirez-Plascencia, Oscar D., Roberto De Luca, Natalia L.S. Machado, Dominique Eghlidi, Mudasir A. Khanday, Sathyajit S. Bandaru, Francesca Raffin, Nina Vujovic, Elda Arrigoni, and Clifford B. Saper. Submitted. “A Hypothalamic Circuit for Circadian Regulation of Corticosterone Secretion”. Research Square rs.3.rs-4718850 (Submitted).

Sivan Almogy

Person: Research Student

Odile D. Peroni, PhD

she/her

Person:

E. Dale Abel, MD, PhD

he/him

Person: William S. Adams Distinguished Professor and Chair, Department of Medicine, David Geffen School of Medicine at UCLA | Los Angeles, CA, Executive Medical Director, UCLA Health | Los Angeles, CA

UCLA profile E. Dale Abel lab

Thomas Chacko Pulinilkunnil, PhD

he/him

Person: Professor, Department of Biochemistry and Molecular Biology, Dalhousie University | Saint John, Canada, Adjunct Professor, University of New Brunswick | Fredericton, Canada, Affilitate Scientist, Saint John Regional Hospital | Saint John, Canada

Dalhousie University profile Lab website