[B22-D-arginine]insulin: synthesis and biological properties
Knorr, Danho, Büllesbach, Gattner, Zahn, King, and Kahn. 1982. “[B22-D-Arginine]insulin: Synthesis and Biological Properties”. Hoppe Seylers Z Physiol Chem 363 (12): 1449-60.
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Subpopulations of antibodies directed against evolutionarily conserved regions of the insulin molecule in insulin-treated patients
Karlsson, Harrison, Kahn, Itin, and Roth. 1982. “Subpopulations of Antibodies Directed Against Evolutionarily Conserved Regions of the Insulin Molecule in Insulin-Treated Patients”. Diabetologia 23 (6): 488-93.
Synthesis and characterization of molecular hybrids of insulin and insulin-like growth factor I. The role of the A-chain extension peptide
King, Kahn, Samuels, Danho, Büllesbach, and Gattner. 1982. “Synthesis and Characterization of Molecular Hybrids of Insulin and Insulin-Like Growth Factor I. The Role of the A-Chain Extension Peptide”. J Biol Chem 257 (18): 10869-73.
Interactions between the receptors for insulin and the insulin-like growth factors on adipocytes
King, Rechler, and Kahn. 1982. “Interactions Between the Receptors for Insulin and the Insulin-Like Growth Factors on Adipocytes”. J Biol Chem 257 (17): 10001-6.
Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.
MH, Solheim, Winnay JN, Batista TM, Molven A, Njølstad PR, and Kahn CR. 2018. “Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis But Not Diabetes.”. Diabetes 67 (7): 1297-1309.
Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes.
AK, Ramirez, Dankel S, Cai W, Sakaguchi M, Kasif S, and Kahn CR. 2019. “Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes.”. Mol. Metabolism 22: 21-36.
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Our plasmids are available through Addgene.
Mentorship and Alumni
Over my 30+ year scientific career, a major focus of the laboratory has been mentoring of students and fellows in the laboratory. At present, there are usually between 12-14 post-doctoral fellows, 1-2 students, and 1 visiting scientist in the laboratory. In total, about 150 fellows have trained in...
Activities
Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha
Almind, Katrine, Laurent Delahaye, Torben Hansen, Emmanuel Van Obberghen, Oluf Pedersen, and Ronald Kahn. 2002. “Characterization of the Met326Ile Variant of Phosphatidylinositol 3-Kinase P85alpha”. Proc Natl Acad Sci U S A 99 (4): 2124-8.