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588 results found

Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells

Publication: Journal Article

Roper, Michael, Wei-jun Qian, Bei Zhang, Rohit Kulkarni, Ronald Kahn, and Robert Kennedy. 2002. “Effect of the Insulin Mimetic L-783,281 on Intracellular Ca2+ and Insulin Secretion from Pancreatic Beta-Cells”. Diabetes 51 Suppl 1: S43-9.

Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival

Publication: Journal Article

Ueki, Kohjiro, David Fruman, Saskia Brachmann, Yu-Hua Tseng, Lewis Cantley, and Ronald Kahn. 2002. “Molecular Balance Between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival”. Mol Cell Biol 22 (3): 965-77.

Absence of insulin receptor substrate-1 expression does not alter GLUT1 or GLUT4 abundance or contraction-stimulated glucose uptake by mouse skeletal muscle

Publication: Journal Article

Dumke, Wetter, Arias, Kahn, and Cartee. 2001. “Absence of Insulin Receptor Substrate-1 Expression Does Not Alter GLUT1 or GLUT4 Abundance or Contraction-Stimulated Glucose Uptake by Mouse Skeletal Muscle”. Horm Metab Res 33 (12): 696-700.

Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance

Publication: Journal Article

Guerra, Navarro, Valverde, Arribas, Brüning, Kozak, Kahn, and Benito. 2001. “Brown Adipose Tissue-Specific Insulin Receptor Knockout Shows Diabetic Phenotype Without Insulin Resistance”. J Clin Invest 108 (8): 1205-13.

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

Publication: Journal Article

Leibiger, Leibiger, Moede, Kemper, Kulkarni, Kahn, Vargas, and Berggren. 2001. “Selective Insulin Signaling through A and B Insulin Receptors Regulates Transcription of Insulin and Glucokinase Genes in Pancreatic Beta Cells”. Mol Cell 7 (3): 559-70.

Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

Publication: Journal Article

Kim, Zisman, Fillmore, Peroni, Kotani, Perret, Zong, et al. 2001. “Glucose Toxicity and the Development of Diabetes in Mice With Muscle-Specific Inactivation of GLUT4”. J Clin Invest 108 (1): 153-60.

Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23

Publication: Journal Article

Tseng, Vicent, J. Zhu, Niu, Adeyinka, Moyers, Watson, and Kahn. 2001. “Regulation of Growth and Tumorigenicity of Breast Cancer Cells by the Low Molecular Weight GTPase Rad and Nm23”. Cancer Res 61 (5): 2071-9.

A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes

Publication: Journal Article

Mauvais-Jarvis, Virkamaki, Michael, Winnay, Zisman, Kulkarni, and Kahn. 2000. “A Model to Explore the Interaction Between Muscle Insulin Resistance and Beta-Cell Dysfunction in the Development of Type 2 Diabetes”. Diabetes 49 (12): 2126-34.

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

Publication: Journal Article

Ueki, Algenstaedt, Mauvais-Jarvis, and Kahn. 2000. “Positive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the P85alpha Regulatory Subunit”. Mol Cell Biol 20 (21): 8035-46.

Cellular compartmentalization in insulin action: altered signaling by a lipid-modified IRS-1

Publication: Journal Article

Kriauciunas, Myers, and Kahn. 2000. “Cellular Compartmentalization in Insulin Action: Altered Signaling by a Lipid-Modified IRS-1”. Mol Cell Biol 20 (18): 6849-59.