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Bio
Dr. Marsel Lino is a post-doctoral research fellow in Dr. C. Ronald Kahn's laboratory at the Joslin Diabetes Center/Harvard Medical School. His research aims to uncover novel inter-organ communication networks by studying tissue-specific exosomal miRNAs in models of obesity and diabetes, with a...
Marsel Lino
Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states
Lino, M., S. Farr, C. Baker, M. Fuller, B. Trigatti, and K. Adeli. 2015. “Intestinal Scavenger Receptor Class B Type I As a Novel Regulator of Chylomicron Production in Healthy and Diet-Induced Obese States”. Am J Physiol Gastrointest Liver Physiol 309 (5): 350-9.
DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification
Ngai, D., M. Lino, K. E. Rothenberg, C. A. Simmons, R. Fernandez-Gonzalez, and M. P. Bendeck. 2020. “DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification”. Arterioscler Thromb Vasc Biol 40 (7): 1763-76.
Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease
Lino, M., D. Ngai, A. Liu, A. Mohabeer, C. Harper, L. L. Caruso, S. A. Schroer, et al. 2020. “Discoidin Domain Receptor 1-Deletion Ameliorates Fibrosis and Promotes Adipose Tissue Beiging, Brown Fat Activity, and Increased Metabolic Rate in a Mouse Model of Cardiometabolic Disease”. Mol Metab 39: 101006.
Cell-Matrix Interactions and Matricrine Signaling in the Pathogenesis of Vascular Calcification
Ngai, D., M. Lino, and M. P. Bendeck. 2018. “Cell-Matrix Interactions and Matricrine Signaling in the Pathogenesis of Vascular Calcification”. Front Cardiovasc Med 5: 174.
Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt-Related Transcription Factor 2 Signaling Axis
Wan, M. H., A. S. Rocca, D. Ngai, N. Shobeiri, G. Hou, C. Ge, R. T. Franceschi, and M. P. Bendeck. 2018. “Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt-Related Transcription Factor 2 Signaling Axis”. Arterioscler Thromb Vasc Biol 38 (8): 1878-89.
Differential major histocompatibility complex class I chain-related A allele associations with skin and joint manifestations of psoriatic disease
Pollock, R., V. Chandran, J. Barrett, L. Eder, F. Pellett, C. Yao, M. Lino, S. Shanmugarajah, V. T. Farewell, and D. D. Gladman. 2011. “Differential Major Histocompatibility Complex Class I Chain-Related A Allele Associations With Skin and Joint Manifestations of Psoriatic Disease”. Tissue Antigens 77 (6): 554-61.
Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance
Naples, M., C. Baker, M. Lino, J. Iqbal, M. M. Hussain, and K. Adeli. 2012. “Ezetimibe Ameliorates Intestinal Chylomicron Overproduction and Improves Glucose Tolerance in a Diet-Induced Hamster Model of Insulin Resistance”. Am J Physiol Gastrointest Liver Physiol 302 (9): 1043-52.