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215 results found

Effect of cartilage oligomeric matrix protein on mesenchymal chondrogenesis in vitro.

Publication: Journal Article

Kipnes, J, A L Carlberg, G A Loredo, J Lawler, R S Tuan, and D J Hall. 2003. “Effect of Cartilage Oligomeric Matrix Protein on Mesenchymal Chondrogenesis in Vitro.”. Osteoarthritis and Cartilage 11 (6): 442-54.

Purification and analysis of thrombospondin-1.

Publication: Journal Article

Yee, Karen O, Mark Duquette, Anna Ludlow, and Jack Lawler. 2003. “Purification and Analysis of Thrombospondin-1.”. Current Protocols in Cell Biology Chapter 10: Unit 10.10.

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

Publication: Journal Article

Agah, Azin, Themis R Kyriakides, Jack Lawler, and Paul Bornstein. 2002. “The Lack of Thrombospondin-1 (TSP1) Dictates the Course of Wound Healing in Double-TSP1/TSP2-Null Mice.”. The American Journal of Pathology 161 (3): 831-9.

Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice.

Publication: Journal Article

Lawler, J, W M Miao, M Duquette, N Bouck, R T Bronson, and R O Hynes. 2001. “Thrombospondin-1 Gene Expression Affects Survival and Tumor Spectrum of P53-Deficient Mice.”. The American Journal of Pathology 159 (5): 1949-56.

Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and -independent mechanisms.

Publication: Journal Article

Miao, W M, W L Seng, M Duquette, P Lawler, C Laus, and J Lawler. 2001. “Thrombospondin-1 Type 1 Repeat Recombinant Proteins Inhibit Tumor Growth through Transforming Growth Factor-Beta-Dependent and -Independent Mechanisms.”. Cancer Research 61 (21): 7830-9.

Thrombospondin-1 and neural crest cell migration.

Publication: Journal Article

Tucker, R P, C Hagios, R Chiquet-Ehrismann, J Lawler, R J Hall, and C A Erickson. 1999. “Thrombospondin-1 and Neural Crest Cell Migration.”. Developmental Dynamics : An Official Publication of the American Association of Anatomists 214 (4): 312-22.

[Sample] RoboEthics: Moral and Ethical Considerations in AI and Robotics

Class

As artificial intelligence and robotics become increasingly prevalent in our society, so does the need for understanding the ethical implications. This course will delve into concepts such as machine autonomy, AI rights, algorithmic bias, and the responsibility of AI creators. Students will evaluate...

[Sample] Culinary Anthropology: The Social Impact of Food

Class

This interdisciplinary course explores the role of food in human societies from prehistoric times to the modern era. By examining food-related rituals, symbolism, economic systems, and power dynamics, students will understand how cuisine shapes and reflects culture. Fieldwork will include visits to...

Research

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The Lawler lab has studied the structure and function of the members of the TSP gene family for more than 50 years. We have focused on the role of TSP-1 in the tumor microenvironment. This research has informed the development of a new cancer therapeutic that is currently being evaluated in murine...

News + Updates

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Our studies on the effects of Fc3TSR in a preclinical model of pancreatic cancer were recently reported at the September AACR meeting in Boston. Abstract A040: Assessing the ability of Fc3TSR to remodel the tumor microenvironment and enhance efficacy of immunotherapeutics and chemotherapy in a...