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Research

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The Kahn Lab is investigating the mechanism of insulin action and its alterations in insulin resistant states, including type 2 diabetes, obesity and metabolic syndrome. There are 3 major areas of research: 1) Insulin action and insulin resistance. In this area we have projects focusing on the...

Insulin action - Mechanisms of insulin resistance

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Differential signaling by insulin and IGF-1 receptors Differences in downstream signaling (IRS proteins/PI 3-kinase) Signaling by unoccupied insulin receptor Cellular and whole animal analysis using KO and KI mice Signaling in unusual tissues, e.g. the gut and brain

Prof C. Ronald Kahn

Person: Professor at Harvard Medical School
C. Ronald Kahn is a world recognized expert in diabetes and obesity research, as well as a preeminent investigator in the area of insulin signal transduction and mechanisms of altered signaling in diabetes and metabolic disease. Dr. Kahn is Senior Investigator, Head of the Section on Integrative...

Jan Heng, PhD

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Current Title/Affiliation: Assistant Professor of Pathology, Harvard Medical School Staff Scientist II, BIDMC Director, Detection Unit, Precision Medicine Core, Harvard Institute of RNA medicine (HiRM)/BIDMC Member, Cancer Research Institute, BIDMC (Translational Therapeutics) Member, Dana Farber...