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Algorithm guides treatment of bacterial keratitis, reduces costs Culturing all suspected cases of bacterial eye infection can be costly, time consuming, and often unnecessary. A new algorithm developed at Mass. Eye and Ear, consisting of a simple set of rules, now helps clinicians in the Emergency...

Do these patients sound familiar? “I’ve worn glasses and contacts for years. My ophthalmologist never mentioned LASIK could be another option.” “Ten years ago, one of my friends had LASIK and she ended up with severe dry eye. I’m not sure I’d want to take the risk.” Precision technology enhances...

Hedonic Capacity, Psychosocial Interventions and Outcomes in Schizophrenia

Dear Colleagues, Research in gene augmentation and genome editing for the treatment of inherited retinal disorders (IRDs) is thriving. It is estimated that IRDs affect about 200,000- 300,000 people in the United States and 4-6 million people worldwide. Most patients with these conditions become...

Gene-Augmentation Therapy Gene therapy typically refers to gene-augmentation therapy. In this approach, a healthy version of the mutated gene is packaged inside an engineered and nonpathogenic form of adeno-associated virus (AAV), with the virus serving as a vector to carry the gene. AAV does not...

Advances in the future may include viral vectors, non-viral vectors, and delivery methods that allow treatment of a greater retinal expanse and an expanded approach to technical challenges related to gene size and disease mechanisms. Genetic therapies for non-retinal ophthalmic diseases are also...