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Where do Harvard Ophthalmology residents complete their internship? As of July 2021, our PGY-1 residents will do a transitional intern year at Newton Wellesley Hospital, with three months of Ophthalmology. Because our program is truly integrated, residents will be part of Mass Eye and Ear for four...

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

Publication: Journal Article

Mauvais-Jarvis, Franck, Kohjiro Ueki, David Fruman, Michael Hirshman, Kei Sakamoto, Laurie Goodyear, Matteo Iannacone, Domenico Accili, Lewis Cantley, and Ronald Kahn. 2002. “Reduced Expression of the Murine P85alpha Subunit of Phosphoinositide 3-Kinase Improves Insulin Signaling and Ameliorates Diabetes”. J Clin Invest 109 (1): 141-9.

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

Publication: Journal Article

Yoon, Puigserver, Chen, Donovan, Wu, Rhee, Adelmant, et al. 2001. “Control of Hepatic Gluconeogenesis through the Transcriptional Coactivator PGC-1”. Nature 413 (6852): 131-8.

Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13

Publication: Journal Article

Magré, Delépine, Khallouf, Gedde-Dahl, Van Maldergem, Sobel, Papp, et al. 2001. “Identification of the Gene Altered in Berardinelli-Seip Congenital Lipodystrophy on Chromosome 11q13”. Nat Genet 28 (4): 365-70.

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

Publication: Journal Article

Leibiger, Leibiger, Moede, Kemper, Kulkarni, Kahn, Vargas, and Berggren. 2001. “Selective Insulin Signaling through A and B Insulin Receptors Regulates Transcription of Insulin and Glucokinase Genes in Pancreatic Beta Cells”. Mol Cell 7 (3): 559-70.

Association of insulin receptor substrate 1 (IRS-1) y895 with Grb-2 mediates the insulin signaling involved in IRS-1-deficient brown adipocyte mitogenesis

Publication: Journal Article

Valverde, Mur, Pons, Alvarez, White, Kahn, and Benito. 2001. “Association of Insulin Receptor Substrate 1 (IRS-1) Y895 With Grb-2 Mediates the Insulin Signaling Involved in IRS-1-Deficient Brown Adipocyte Mitogenesis”. Mol Cell Biol 21 (7): 2269-80.

Unbalanced expression of the different subunits of elongation factor 1 in diabetic skeletal muscle

Publication: Journal Article

Reynet, and Kahn. 2001. “Unbalanced Expression of the Different Subunits of Elongation Factor 1 in Diabetic Skeletal Muscle”. Proc Natl Acad Sci U S A 98 (6): 3422-7.

Putting the genes for type II diabetes on the map

Publication: Journal Article

Almind, Doria, and Kahn. 2001. “Putting the Genes for Type II Diabetes on the Map”. Nat Med 7 (3): 277-9.

Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus

Publication: Journal Article

Kahn, Brüning, Michael, and Kulkarni. 2000. “Knockout Mice Challenge Our Concepts of Glucose Homeostasis and the Pathogenesis of Diabetes Mellitus”. J Pediatr Endocrinol Metab 13 Suppl 6: 1377-84.

Understanding the pathogenesis and treatment of insulin resistance and type 2 diabetes mellitus: what can we learn from transgenic and knockout mice?

Publication: Journal Article

Mauvais-Jarvis, and Kahn. 2000. “Understanding the Pathogenesis and Treatment of Insulin Resistance and Type 2 Diabetes Mellitus: What Can We Learn from Transgenic and Knockout Mice?”. Diabetes Metab 26 (6): 433-48.