New concepts and perspectives in decompensated cirrhosis.
Jalan, Rajiv, and Gyongyi Szabo. 2021. “New Concepts and Perspectives in Decompensated Cirrhosis.”. Journal of Hepatology 75 Suppl 1 (Suppl 1): S1-S2.
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Steatosis, inflammasome upregulation, and fibrosis are attenuated in miR-155 deficient mice in a high fat-cholesterol-sugar diet-induced model of NASH.
Bala, Shashi, Michal Ganz, Mrigya Babuta, Yuan Zhuang, Timea Csak, Charles D Calenda, and Gyongyi Szabo. 2021. “Steatosis, Inflammasome Upregulation, and Fibrosis Are Attenuated in MiR-155 Deficient Mice in a High Fat-Cholesterol-Sugar Diet-Induced Model of NASH.”. Laboratory Investigation; A Journal of Technical Methods and Pathology 101 (12): 1540-49.
Review article: vascular effects of PPARs in the context of NASH.
Guixé-Muntet, Sergi, Louise Biquard, Gyongyi Szabo, Jean-François Dufour, Frank Tacke, Sven Francque, Pierre-Emmanuel Rautou, and Jordi Gracia-Sancho. 2022. “Review Article: Vascular Effects of PPARs in the Context of NASH.”. Alimentary Pharmacology & Therapeutics 56 (2): 209-23.
Reply.
Szabo, Gyongyi, Mack Mitchell, Craig J McClain, Srinivasan Dasarathy, Bruce Barton, Arthur J McCullough, Laura E Nagy, et al. 2022. “Reply.”. Hepatology (Baltimore, Md.) 76 (5): E114-E115.
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Zhang, Tao, Daichao Xu, Jianping Liu, Min Wang, Li-Juan Duan, Min Liu, Huyan Meng, et al. 2023. “Prolonged Hypoxia Alleviates Prolyl Hydroxylation-Mediated Suppression of RIPK1 to Promote Necroptosis and Inflammation.”. Nature Cell Biology 25 (7): 950-62.
Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease.
Mrdjen, Marko, Emily Huang, Vai Pathak, Annette Bellar, Nicole Welch, Jaividhya Dasarathy, David Streem, et al. 2023. “Dysregulated Meta-Organismal Metabolism of Aromatic Amino Acids in Alcohol-Associated Liver Disease.”. Hepatology Communications 7 (11).
Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1.
Zhuang, Yuan, Martí Ortega-Ribera, Prashanth Thevkar Nagesh, Radhika Joshi, Huihui Huang, Yanbo Wang, Adam Zivny, Jeeval Mehta, Samir M Parikh, and Gyongyi Szabo. 2024. “Bile Acid-Induced IRF3 Phosphorylation Mediates Cell Death, Inflammatory Responses, and Fibrosis in Cholestasis-Induced Liver and Kidney Injury via Regulation of ZBP1.”. Hepatology (Baltimore, Md.) 79 (4): 752-67.
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis.
Taiwo, Moyinoluwa, Emily Huang, Vai Pathak, Annette Bellar, Nicole Welch, Jaividhya Dasarathy, David Streem, et al. 2024. “Proteomics Identifies Complement Protein Signatures in Patients With Alcohol-Associated Hepatitis.”. JCI Insight 9 (9).
A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis.
Babuta, Mrigya, Caroline Morel, Marcelle de Carvalho Ribeiro, Aditi Ashish Datta, Charles Calenda, Christopher Copeland, Imad Nasser, and Gyongyi Szabo. 2024. “A Novel Experimental Model of MetALD in Male Mice Recapitulates Key Features of Severe Alcohol-Associated Hepatitis.”. Hepatology Communications 8 (7).
Efficacy and Safety of Erenumab for Nonopioid Medication Overuse Headache in Chronic Migraine: A Phase 4, Randomized, Placebo-Controlled Trial.
Tepper, Stewart J, David W Dodick, Michel Lanteri-Minet, David Dolezil, Raquel Gil-Gouveia, Christian Lucas, Karolina Piasecka-Stryczynska, et al. 2024. “Efficacy and Safety of Erenumab for Nonopioid Medication Overuse Headache in Chronic Migraine: A Phase 4, Randomized, Placebo-Controlled Trial.”. JAMA Neurology.