New mechanisms of glucocorticoid-induced insulin resistance: make no bones about it
Ferris, Heather, and Ronald Kahn. 2012. “New Mechanisms of Glucocorticoid-Induced Insulin Resistance: Make No Bones about It”. J Clin Invest 122 (11): 3854-7.
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Turning on brown fat and muscle metabolism: hedging your bets
Lee, Kevin, and Ronald Kahn. 2012. “Turning on Brown Fat and Muscle Metabolism: Hedging Your Bets”. Cell 151 (2): 248-50.
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
Zarse, Kim, Sebastian Schmeisser, Marco Groth, Steffen Priebe, Gregor Beuster, Doreen Kuhlow, Reinhard Guthke, Matthias Platzer, Ronald Kahn, and Michael Ristow. 2012. “Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal”. Cell Metab 15 (4): 451-65.
A guide to analysis of mouse energy metabolism
Tschöp, Matthias, John Speakman, Jonathan Arch, Johan Auwerx, Jens Brüning, Lawrence Chan, Robert Eckel, et al. 2011. “A Guide to Analysis of Mouse Energy Metabolism”. Nat Methods 9 (1): 57-63.
Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity
Wan, Min, Rachael Easton, Catherine Gleason, Bobby Monks, Kohjiro Ueki, Ronald Kahn, and Morris Birnbaum. 2012. “Loss of Akt1 in Mice Increases Energy Expenditure and Protects Against Diet-Induced Obesity”. Mol Cell Biol 32 (1): 96-106.
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
Hirschey, Matthew, Tadahiro Shimazu, Enxuan Jing, Carrie Grueter, Amy Collins, Bradley Aouizerat, Alena Stančáková, et al. 2011. “SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome”. Mol Cell 44 (2): 177-90.
Mir193b-365 is essential for brown fat differentiation
Sun, Lei, Huangming Xie, Marcelo Mori, Ryan Alexander, Bingbing Yuan, Shilpa Hattangadi, Qingqing Liu, Ronald Kahn, and Harvey Lodish. 2011. “Mir193b-365 Is Essential for Brown Fat Differentiation”. Nat Cell Biol 13 (8): 958-65.
PI 3-kinase regulatory subunits as regulators of the unfolded protein response
Winnay, Jonathon, and Ronald Kahn. 2011. “PI 3-Kinase Regulatory Subunits As Regulators of the Unfolded Protein Response”. Methods Enzymol 490: 147-58.
A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis
Boucher, Jeremie, Yazmin Macotela, Olivier Bezy, Marcelo Mori, Kristina Kriauciunas, and Ronald Kahn. 2010. “A Kinase-Independent Role for Unoccupied Insulin and IGF-1 Receptors in the Control of Apoptosis”. Sci Signal 3 (151): ra87.
A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease
Mori, Marcelo, Manway Liu, Olivier Bezy, Katrine Almind, Hagit Shapiro, Simon Kasif, and Ronald Kahn. 2010. “A Systems Biology Approach Identifies Inflammatory Abnormalities Between Mouse Strains Prior to Development of Metabolic Disease”. Diabetes 59 (11): 2960-71.