Reactive oxygen species: The Yin and Yang in (auto-)immunity
Scherlinger, M., and G. C. Tsokos. 2021. “Reactive Oxygen Species: The Yin and Yang in (auto-)immunity”. Autoimmun Rev 20: 102869.
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T cell Metabolism in Lupus
Vukelic, M., M. Kono, and G. C. Tsokos. 2020. “T Cell Metabolism in Lupus”. Immunometabolism 2.
Maintenance of Efficacy and Safety of Ustekinumab Through One Year in a Phase II Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Crossover Trial of Patients With Active Systemic Lupus Erythematosus
van Vollenhoven, R. F., B. H. Hahn, G. C. Tsokos, P. Lipsky, K. Fei, R. M. Gordon, I. Gregan, K. H. Lo, M. Chevrier, and S. Rose. 2020. “Maintenance of Efficacy and Safety of Ustekinumab Through One Year in a Phase II Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Crossover Trial of Patients With Active Systemic Lupus Erythematosus”. Arthritis Rheumatol 72: 761-68.
Complement Deposition on the Surface of RBC After Trauma Serves a Biomarker of Moderate Trauma Severity: A Prospective Study
Satyam, A., K. Andreo, P. H. Lapchak, J. J. Dalle Lucca, R. B. Davis, M. G. Tsokos, N. I. Shapiro, and G. C. Tsokos. 2020. “Complement Deposition on the Surface of RBC After Trauma Serves a Biomarker of Moderate Trauma Severity: A Prospective Study”. Shock 53: 16-23.
Protein phosphatase 2A B55beta limits CD8+ T cell lifespan following cytokine withdrawal
Rodriguez-Rodriguez, N., I. K. Madera-Salcedo, J. A. Cisneros-Segura, H. B. Garcia-Gonzalez, S. A. Apostolidis, A. Saint-Martin, M. Esquivel-Velazquez, et al. 2020. “Protein Phosphatase 2A B55beta Limits CD8+ T Cell Lifespan Following Cytokine Withdrawal”. J Clin Invest 130: 5989-6004.
Serine/threonine phosphatase PP2A is essential for optimal B cell function
Meidan, E., H. Li, W. Pan, M. Kono, S. Yu, V. C. Kyttaris, C. Ioannidis, et al. 2020. “Serine/Threonine Phosphatase PP2A Is Essential for Optimal B Cell Function”. JCI Insight 5.
A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury
Kost-Alimova, M., E. H. Sidhom, A. Satyam, B. T. Chamberlain, M. Dvela-Levitt, M. Melanson, S. L. Alper, et al. 2020. “A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib As a Candidate for Rapid Repurposing for Acute Lung Injury”. Cell Rep Med 1: 100137.
The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections
Katsuyama, E., A. Suarez-Fueyo, S. J. Bradley, M. Mizui, A. V. Marin, L. Mulki, S. Krishfield, et al. 2020. “The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients With SLE Prone to Infections”. Cell Rep 30: 112-123 e4.
Cancer immunosurveillance by CD8 T cells
Crispin, J. C., and G. C. Tsokos. 2020. “Cancer Immunosurveillance by CD8 T Cells”. F1000Res 9.
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
Alimova, M., E. H. Sidhom, A. Satyam, M. Dvela-Levitt, M. Melanson, B. T. Chamberlain, S. L. Alper, et al. 2020. “A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib As a Candidate for Rapid Repurposing for Acute Lung Injury During the COVID-19 Pandemic”. BioRxiv.