Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess
Barbour, Linda, Shaikh Mizanoor Rahman, Inga Gurevich, Wayne Leitner, Stephanie Fischer, Michael Roper, Trina Knotts, et al. 2005. “Increased P85alpha Is a Potent Negative Regulator of Skeletal Muscle Insulin Signaling and Induces in Vivo Insulin Resistance Associated With Growth Hormone Excess”. J Biol Chem 280 (45): 37489-94.