News Roundup: April - June 2024
News Roundup: April - June 2024
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An Artificial Intelligence Algorithm for Detection of Severe Aortic Stenosis: A Clinical Cohort Study.
Strom, Jordan B, David Playford, Simon Stewart, and Geoff Strange. 2024. “An Artificial Intelligence Algorithm for Detection of Severe Aortic Stenosis: A Clinical Cohort Study.”. JACC. Advances 3 (9): 101176.
Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin.
Dhakal, Bibek, Appi Mandhapati, Pradheep Eradi, Simon Park, Kirby Fibben, Kaicheng Li, Ashley DeYong, et al. 2024. “Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin.”. Journal of the American Chemical Society 146 (25): 17414-27.
Indolyl-chalcone derivatives trigger apoptosis in cisplatin-resistant mesothelioma cells through aberrant tubulin polymerization and deregulation of microtubule-associated proteins.
Steinlein, Sophia, Frank Essmann, Amanda Franceschini Ghilardi, Heike Horn, Julia Schüler, Angelika Hausser, Lijun Sun, German Ott, and Claudia Kalla. 2023. “Indolyl-Chalcone Derivatives Trigger Apoptosis in Cisplatin-Resistant Mesothelioma Cells through Aberrant Tubulin Polymerization and Deregulation of Microtubule-Associated Proteins.”. Frontiers in Oncology 13: 1190988.
A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis.
Wong, Daniel J, Diane D Park, Simon S Park, Carolyn A Haller, Jiaxuan Chen, Erbin Dai, Liying Liu, et al. 2021. “A PSGL-1 Glycomimetic Reduces Thrombus Burden Without Affecting Hemostasis.”. Blood 138 (13): 1182-93.
Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.
Jernigan, Finith E, Jun-Ichi Hanai, Vikas P Sukhatme, and Lijun Sun. 2017. “Discovery of Furan Carboxylate Derivatives As Novel Inhibitors of ATP-Citrate Lyase via Virtual High-Throughput Screening.”. Bioorganic & Medicinal Chemistry Letters 27 (4): 929-35.
A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.
Radomska, Hanna S, Finith Jernigan, Sohei Nakayama, Susan E Jorge, Lijun Sun, Daniel G Tenen, and Susumu S Kobayashi. 2015. “A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.”. Journal of Biomolecular Screening 20 (9): 1150-9.
Syntheses and antitumor activities of N'1,N'3-dialkyl-N'1,N'3-di-(alkylcarbonothioyl) malonohydrazide: the discovery of elesclomol.
Chen, Shoujun, Lijun Sun, Keizo Koya, Noriaki Tatsuta, Zhiqiang Xia, Timothy Korbut, Zhenjian Du, et al. 2013. “Syntheses and Antitumor Activities of N’1,N’3-Dialkyl-N’1,N’3-Di-(alkylcarbonothioyl) Malonohydrazide: The Discovery of Elesclomol.”. Bioorganic & Medicinal Chemistry Letters 23 (18): 5070-6.
The synthesis of neoglycophospholipid conjugates via reductive amination of omega-oxoalkylglycosides and phosphatidylethanolamines.
Sun, L, and E L Chaikof. 1998. “The Synthesis of Neoglycophospholipid Conjugates via Reductive Amination of Omega-Oxoalkylglycosides and Phosphatidylethanolamines.”. Carbohydrate Research 307 (1-2): 77-81.