SPAR, a lncRNA encoded mTORC1 inhibitor.
Matsumoto, Akinobu, John G Clohessy, and Pier Paolo Pandolfi. 2017. “SPAR, a LncRNA Encoded MTORC1 Inhibitor.”. Cell Cycle (Georgetown, Tex.) 16 (9): 815-16.
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The pleiotropic role of non-coding genes in development and cancer.
Pasut, Alessandra, Akinobu Matsumoto, John G Clohessy, and Pier Paolo Pandolfi. 2016. “The Pleiotropic Role of Non-Coding Genes in Development and Cancer.”. Current Opinion in Cell Biology 43: 104-13.
NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.
Rau, Rachel, Daniel Magoon, Sarah Greenblatt, Li Li, Colleen Annesley, Amy S Duffield, David Huso, et al. 2014. “NPMc+ Cooperates With Flt3/ITD Mutations to Cause Acute Leukemia Recapitulating Human Disease.”. Experimental Hematology 42 (2): 101-13.e5.
The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells.
Fagoonee, Sharmila, Claudia Bearzi, Ferdinando Di Cunto, John G Clohessy, Roberto Rizzi, Markus Reschke, Emanuela Tolosano, et al. 2013. “The RNA Binding Protein ESRP1 Fine-Tunes the Expression of Pluripotency-Related Factors in Mouse Embryonic Stem Cells.”. PloS One 8 (8): e72300.
Subtle variations in Pten dose determine cancer susceptibility.
Alimonti, Andrea, Arkaitz Carracedo, John G Clohessy, Lloyd C Trotman, Caterina Nardella, Ainara Egia, Leonardo Salmena, et al. 2010. “Subtle Variations in Pten Dose Determine Cancer Susceptibility.”. Nature Genetics 42 (5): 454-8.
Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer.
Montanaro, L, M Brigotti, J Clohessy, S Barbieri, C Ceccarelli, D Santini, M Taffurelli, et al. 2006. “Dyskerin Expression Influences the Level of Ribosomal RNA Pseudo-Uridylation and Telomerase RNA Component in Human Breast Cancer.”. The Journal of Pathology 210 (1): 10-8.
Delivery Unit from Precision RNA Medicine Core Powers New RNA-Based Cancer Therapy
In a recent Nature Communications study, Dr. Annalisa Di Ruscio and team introduced aptaDiR, a novel RNA therapeutic engineered to silence DNMT1 and reverse abnormal DNA methylation in cancer. Delivered via lipid nanoparticles, aptaDiR reactivated tumor-suppressor genes and significantly reduced...
Extramural US Federal Research Grants For Health Outcomes Associated With Climate Change Inadequate, Too Narrow In Focus.
Sorensen, Cecilia, Caleb Dresser, Arjun Balakumar, Stefan Wheat, Elizabeth Yates, James P Healy, Connor Brown, et al. 2023. “Extramural US Federal Research Grants For Health Outcomes Associated With Climate Change Inadequate, Too Narrow In Focus.”. Health Affairs (Project Hope) 42 (9): 1289-97.
Dresser C, Storr L, Leaning J. Disasters and Emergency Planning. In: International Encyclopedia of Public Health (Third Edition), Editor(s): Stella R. Quah. Pages 759-772.
“Dresser C, Storr L, Leaning J. Disasters and Emergency Planning. In: International Encyclopedia of Public Health (Third Edition), Editor(s): Stella R. Quah. Pages 759-772.”. 2025. International Encyclopedia of Public Health (Third Edition), Editor(s): Stella R. Qua.