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Reliability of breast stromal markers immunofluorescent staining: pathologist assessment compared to quantitative image analysis

Publication: Journal Article

Yaghjyan, Lusine, Yujing J. Heng, Yaileen D Guzman-Arocho, Graham Colditz, Brian R Sardella, Ann Fu, K Patel, Bernard A Rosner, Maisey Ratcliff, and Rulla M Tamimi. Submitted. “Reliability of Breast Stromal Markers Immunofluorescent Staining: Pathologist Assessment Compared to Quantitative Image Analysis”. Submitted, Submitted.

Jan Heng, PhD

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Current Title/Affiliation: Assistant Professor of Pathology, Harvard Medical School Staff Scientist II, BIDMC Director, Detection Unit, Precision Medicine Core, Harvard Institute of RNA medicine (HiRM)/BIDMC Member, Cancer Research Institute, BIDMC (Translational Therapeutics) Member, Dana Farber...

Associations of alcohol consumption with expression of CD44, CD24, and ALDH1A1 stem cell markers in benign breast biopsy samples

Publication: Journal Article

Ratcliffe, Maisey, Lusine Yaghjyan, Yujing J Heng, Gabrielle M Baker, Bernard A Rosner, and Rulla M Tamimi. 2025. “Associations of Alcohol Consumption With Expression of CD44, CD24, and ALDH1A1 Stem Cell Markers in Benign Breast Biopsy Samples”. Cancer Causes Control 36: 1489-97.

Genomic and Transcriptomic Landscape and Determinants of Response of BRCA-related Breast Cancers Treated with Neoadjuvant Chemotherapy (TBCRC 031)

Publication: Journal Article

Batalini, Felipe, Nadine Tung, Tae-Hee Clara Kim, Xanthi-Lida Katopodi, Nikolas Kalavros, Antuan Tran, Dimitra Karagkouni, et al. Submitted. “Genomic and Transcriptomic Landscape and Determinants of Response of BRCA-Related Breast Cancers Treated With Neoadjuvant Chemotherapy (TBCRC 031)”. Submitted, Submitted.

MicroRNA spatial profiling for assessing drug efficacy in BRCA1-related triple-negative breast tumors

Publication: Journal Article

Mohd, Omar N, Lin Wang, Brian R Sardella, David Jou, Gerburg M Wulf, Frank J Slack, Yujing J Heng, and Patrick S Doyle. 2026. “MicroRNA Spatial Profiling for Assessing Drug Efficacy in BRCA1-Related Triple-Negative Breast Tumors”. BioRxiv, 2026.01.12.698824.

Masculinizing Testosterone Therapy Reduces the Incidence of PIK3CA-Mutant/ER+ Breast Cancer but Not BRCA1-Associated Triple-Negative Breast Cancer

Publication: Journal Article

Wang, Lin, Brian R Sardella, Abhishek Thavamani, Erica S Massicott, Vanessa C Bret-Mounet, Gabrielle M Baker, Yaileen D Guzman-Arocho, et al. 2025. “Masculinizing Testosterone Therapy Reduces the Incidence of PIK3CA-Mutant/ER+ Breast Cancer But Not BRCA1-Associated Triple-Negative Breast Cancer”. MedRxiv, 2025.09.15.25335324.

AACR 2026 Meeting Abstracts

News: February 04, 2026

Dr. Heng will have 6 abstracts at AACR: Bockorny et al. Real-world evidence of KMT2C mutation as a biomarker of sensitivity to platinum-based therapy in solid cancers. (Oral) Liu et al. MiR-362-3p enhances platinum response in breast cancer. Guzman-Arocho et al. Associations of Stromal Markers with...