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588 results found

Signal transducer and activator of transcription 3 and the phosphatidylinositol 3-kinase regulatory subunits p55α and p50α regulate autophagy in vivo

Publication: Journal Article

Pensa, Sara, Bethan Lloyd-Lewis, Timothy Sargeant, Henrike Resemann, Ronald Kahn, and Christine Watson. 2014. “Signal Transducer and Activator of Transcription 3 and the Phosphatidylinositol 3-Kinase Regulatory Subunits P55α and P50α Regulate Autophagy in Vivo”. FEBS J 281 (20): 4557-67.

Insulin receptor signaling in normal and insulin-resistant states

Publication: Journal Article

Boucher, Jeremie, Andre Kleinridders, and Ronald Kahn. 2014. “Insulin Receptor Signaling in Normal and Insulin-Resistant States”. Cold Spring Harb Perspect Biol 6 (1).

[B22-D-arginine]insulin: synthesis and biological properties

Publication: Journal Article

Knorr, Danho, Büllesbach, Gattner, Zahn, King, and Kahn. 1982. “[B22-D-Arginine]insulin: Synthesis and Biological Properties”. Hoppe Seylers Z Physiol Chem 363 (12): 1449-60.

Subpopulations of antibodies directed against evolutionarily conserved regions of the insulin molecule in insulin-treated patients

Publication: Journal Article

Karlsson, Harrison, Kahn, Itin, and Roth. 1982. “Subpopulations of Antibodies Directed Against Evolutionarily Conserved Regions of the Insulin Molecule in Insulin-Treated Patients”. Diabetologia 23 (6): 488-93.

Synthesis and characterization of molecular hybrids of insulin and insulin-like growth factor I. The role of the A-chain extension peptide

Publication: Journal Article

King, Kahn, Samuels, Danho, Büllesbach, and Gattner. 1982. “Synthesis and Characterization of Molecular Hybrids of Insulin and Insulin-Like Growth Factor I. The Role of the A-Chain Extension Peptide”. J Biol Chem 257 (18): 10869-73.

Interactions between the receptors for insulin and the insulin-like growth factors on adipocytes

Publication: Journal Article

King, Rechler, and Kahn. 1982. “Interactions Between the Receptors for Insulin and the Insulin-Like Growth Factors on Adipocytes”. J Biol Chem 257 (17): 10001-6.

Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.

Publication: Journal Article

MH, Solheim, Winnay JN, Batista TM, Molven A, Njølstad PR, and Kahn CR. 2018. “Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis But Not Diabetes.”. Diabetes 67 (7): 1297-1309.

Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes.

Publication: Journal Article

AK, Ramirez, Dankel S, Cai W, Sakaguchi M, Kasif S, and Kahn CR. 2019. “Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes.”. Mol. Metabolism 22: 21-36.

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Our plasmids are available through Addgene.

Over my 30+ year scientific career, a major focus of the laboratory has been mentoring of students and fellows in the laboratory. At present, there are usually between 12-14 post-doctoral fellows, 1-2 students, and 1 visiting scientist in the laboratory. In total, about 150 fellows have trained in...