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Menadione-Induced DNA Damage Leads to Mitochondrial Dysfunction and Fragmentation During Rosette Formation in Fuchs Endothelial Corneal Dystrophy.

Halilovic, Adna, Thore Schmedt, Anne-Sophie Benischke, Cecily Hamill, Yuming Chen, Janine Hertzog Santos, and Ula Jurkunas. 2016. “Menadione-Induced DNA Damage Leads to Mitochondrial Dysfunction and Fragmentation During Rosette Formation in Fuchs Endothelial Corneal Dystrophy.”. Antioxid Redox Signal 24 (18): 1072-83.

When is Genetic Testing Appropriate?

Many inherited diseases are caused by mutations in a single gene (Mendelian disorder), and detection of the responsible mutation can predict development of the disease with relatively high accuracy. If your clinical findings suggest the presence of an inherited eye disease, such as those described...