Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha 1, 4-glycosyltransferases conserved in plants, insects, and mammals.
Keusch, Manzella, Nyame, Cummings, and Baenziger. 2000. “Cloning of Gb3 Synthase, the Key Enzyme in Globo-Series Glycosphingolipid Synthesis, Predicts a Family of Alpha 1, 4-Glycosyltransferases Conserved in Plants, Insects, and Mammals.”. J Biol Chem 275 (33): 25315-21.