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James M. Anderson, M.D., Ph.D.

James M. Anderson, M.D., Ph.D. National Institutes of Health (NIH) | Senior Investigator for Laboratory of Tight Junction Structure and Function Dynamic coupling of the tight junction to the cytoskeleton

Welcome to the Harvard Digestive Disease Center

Welcome to the Harvard Digestive Diseases Center (HDDC) The HDDC is an NIH-funded Center that serves a broad community of scientists conducting basic and translational research relevant to the gastrointestinal tract. The HDDC facilitates multidisciplinary research and collaboration among independent...

Welcome to the Harvard Digestive Disease Center

Welcome to the Harvard Digestive Diseases Center (HDDC) The HDDC is an NIH-funded Center that serves a broad community of scientists conducting basic and translational research relevant to the gastrointestinal tract. The HDDC facilitates multidisciplinary research and collaboration among independent...

Epithelial and Stem Cells

The HDDC members active in this group are basic cell and developmental biologists, including a strong group of stem cell and tissue engineering biologists, who are broadening and deepening the longstanding focus of the HDDC on intestinal epithelial cell biology. Leaders: David Breault, MD, PhD &...

Mucosal Immunology

Theme 2 investigators are basic scientists probing the cellular and molecular basis of adaptive and innate immunity critical to mucosal defense. Given the intense relationship between the immune system and lumenal microbes that plays out across the intestinal epithelial barrier, it is not surprising...

Imaging Services - BIDMC

Imagine Core B- BIDMC Services Histology BIDMC: https://www.bidmc.org/research/core-facilities/histology-confocal-em/histology-core Confocal/Immunostaining BIDMC: https://www.bidmc.org/research/core-facilities/histology-confocal-em/confocal-imaging-core Electron Microscopy BIDMC: https://www.bidmc...

Affiliate Members

HDDC MEMBER INSTITUTION HDDC Research Focus Banks, Peter, MD BWH Clinical and Translational Research Basan ,Marcus PhD BCH Gut Microbiome and Metabolism Benoit, Christophe HMS Innate and Adaptive Mucosal immunology,Microbial Pathogenesis Bousvaros, Athos, MD, MPH BCH Clinical and Translational...

Internal Advisory Board

Fred Alt, PhD Boston Children's Hospital Charlie Serhan, PhD Brigham and Women's Hospital Mark Zeidel, MD Beth Israel Deaconness Medical Center David Golan, MD, PhD Harvard Medical School

Core Services

Overview of HDDC Cores and Services Use the links for detailed descriptions, locations and contact information. Biomedical CORE B: Microscopy and Histopathology Histology(paraffin and frozen sections) Electron and Confocal Microscopy Photodocumentation and Widefield Microscopy Advanced Imaging...

Polarized Epithelial Cell Culture

Core Technician: Sierra Anderson Services Polarized epithelial cell lines maintained and available: human intestinal T84, HT29, Caco2-BBe, and SKCO-15; canine renal MDCK I and MDCK II cells; porcine kidney LL-CPK cells Second site storage available for specialized cell lines prepared by HDDC members...