Insulin receptor knockout mice
Kitamura, Tadahiro, Ronald Kahn, and Domenico Accili. 2003. “Insulin Receptor Knockout Mice”. Annu Rev Physiol 65: 313-32.
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Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha
Hallmann, Daniel, Katja Trümper, Heidi Trusheim, Kohjiro Ueki, Ronald Kahn, Lewis Cantley, David Fruman, and Dieter Hörsch. 2003. “Altered Signaling and Cell Cycle Regulation in Embryonal Stem Cells With a Disruption of the Gene for Phosphoinositide 3-Kinase Regulatory Subunit P85alpha”. J Biol Chem 278 (7): 5099-108.
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
Crackower, Michael, Gavin Oudit, Ivona Kozieradzki, Renu Sarao, Hui Sun, Takehiko Sasaki, Emilio Hirsch, et al. 2002. “Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways”. Cell 110 (6): 737-49.
beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass
Kulkarni, Holzenberger, Shih, Ozcan, Stoffel, Magnuson, and Kahn. 2002. “Beta-Cell-Specific Deletion of the Igf1 Receptor Leads to Hyperinsulinemia and Glucose Intolerance But Does Not Alter Beta-Cell Mass”. Nat Genet 31 (1): 111-5.
Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice
Reis, Felipe, Jéssica Branquinho, Bruna Brandão, Beatriz Guerra, Ismael Silva, Andrea Frontini, Thomas Thomou, et al. 2016. “Fat-Specific Dicer Deficiency Accelerates Aging and Mitigates Several Effects of Dietary Restriction in Mice”. Aging (Albany NY) 8 (6): 1201-22.
Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function
Burkart, Alison, Kelly Tan, Laura Warren, Salvatore Iovino, Katelyn Hughes, Ronald Kahn, and Mary-Elizabeth Patti. 2016. “Insulin Resistance in Human IPS Cells Reduces Mitochondrial Size and Function”. Sci Rep 6: 22788.
Effect of cholesterol reduction on receptor signaling in neurons
Fukui, Kenji, Heather Ferris, and Ronald Kahn. 2015. “Effect of Cholesterol Reduction on Receptor Signaling in Neurons”. J Biol Chem 290 (44): 26383-92.
Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism
Li, Mengyao, Sara Vienberg, Olivier Bezy, Brian O’Neill, and Ronald Kahn. 2015. “Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism”. Diabetes 64 (12): 4023-32.
Signal transducer and activator of transcription 3 and the phosphatidylinositol 3-kinase regulatory subunits p55α and p50α regulate autophagy in vivo
Pensa, Sara, Bethan Lloyd-Lewis, Timothy Sargeant, Henrike Resemann, Ronald Kahn, and Christine Watson. 2014. “Signal Transducer and Activator of Transcription 3 and the Phosphatidylinositol 3-Kinase Regulatory Subunits P55α and P50α Regulate Autophagy in Vivo”. FEBS J 281 (20): 4557-67.
Insulin receptor signaling in normal and insulin-resistant states
Boucher, Jeremie, Andre Kleinridders, and Ronald Kahn. 2014. “Insulin Receptor Signaling in Normal and Insulin-Resistant States”. Cold Spring Harb Perspect Biol 6 (1).