Evidence for a circulating islet cell growth factor in insulin-resistant states
Flier, Kulkarni, and Kahn. 2001. “Evidence for a Circulating Islet Cell Growth Factor in Insulin-Resistant States”. Proc Natl Acad Sci U S A 98 (13): 7475-80.
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Frataxin activates mitochondrial energy conversion and oxidative phosphorylation
Ristow, Pfister, Yee, Schubert, Michael, Zhang, Ueki, Michael, Lowell, and Kahn. 2000. “Frataxin Activates Mitochondrial Energy Conversion and Oxidative Phosphorylation”. Proc Natl Acad Sci U S A 97 (22): 12239-43.
Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans
Hebinck, Hardt, Schöls, Vorgerd, Briedigkeit, Kahn, and Ristow. 2000. “Heterozygous Expansion of the GAA Tract of the X25/Frataxin Gene Is Associated With Insulin Resistance in Humans”. Diabetes 49 (9): 1604-7.
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
Michael, Kulkarni, Postic, Previs, Shulman, Magnuson, and Kahn. 2000. “Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction”. Mol Cell 6 (1): 87-97.
Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice
Wojtaszewski, Higaki, Hirshman, Michael, Dufresne, Kahn, and Goodyear. 1999. “Exercise Modulates Postreceptor Insulin Signaling and Glucose Transport in Muscle-Specific Insulin Receptor Knockout Mice”. J Clin Invest 104 (9): 1257-64.
Role of the transmembrane domain and flanking amino acids in internalization and down-regulation of the insulin receptor
Yamada, Carpentier, Cheatham, Goncalves, Shoelson, and Kahn. 1995. “Role of the Transmembrane Domain and Flanking Amino Acids in Internalization and Down-Regulation of the Insulin Receptor”. J Biol Chem 270 (7): 3115-22.
Picking a research problem. The critical decision
Kahn. 1994. “Picking a Research Problem. The Critical Decision”. N Engl J Med 330 (21): 1530-3.
The level of insulin receptor tyrosine kinase activity modulates the activities of phosphatidylinositol 3-kinase, microtubule-associated protein, and S6 kinases
Wilden, and Kahn. 1994. “The Level of Insulin Receptor Tyrosine Kinase Activity Modulates the Activities of Phosphatidylinositol 3-Kinase, Microtubule-Associated Protein, and S6 Kinases”. Mol Endocrinol 8 (5): 558-67.
Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin, and dexamethasone
Saad, Folli, Araki, Hashimoto, Csermely, and Kahn. 1994. “Regulation of Insulin Receptor, Insulin Receptor Substrate-1 and Phosphatidylinositol 3-Kinase in 3T3-F442A Adipocytes. Effects of Differentiation, Insulin, and Dexamethasone”. Mol Endocrinol 8 (5): 545-57.
The insulin signaling system
White, and Kahn. 1994. “The Insulin Signaling System”. J Biol Chem 269 (1): 1-4.