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Pgc-1α overexpression downregulates pitx3 and increases susceptibility to MPTP toxicity associated with decreased bdnf

Publication: Journal Article

Clark, J, JM Silvaggi, T Kiselak, K Zheng, E Clore, Y Dai, CE Bass, and DK Simon. 2012. “Pgc-1α Overexpression Downregulates Pitx3 and Increases Susceptibility to MPTP Toxicity Associated With Decreased Bdnf”. PLoS ONE.

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Blog: May 16, 2023

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Quis autem repudiandae consequatur illo doloribus ratione. Omnis amet aut vitae ad accusamus. Tempore Quia Ut Ullam Nihil Aspernatur Eos. Debitis omnis ut dolore excepturi vel doloremque odit provident. Exercitationem maxime sit. Sapiente temporibus et magnam facilis impedit accusantium deserunt...

Press release in BIDMC News

News: November 14, 2023

"Researchers Halt Progression in Parkinson's Disease Mouse Model" discussed in BIDMC press release Jacqueline Mitchell reports on the Simon Lab's contributions to a deeper understanding of the mechanisms underlying Parkinson's Disease and the best novel targets to investigate potential treatments...

Postdoctoral fellow Dr. Michele Persico (currently at Emory University) presented our work on VPS35 at the American Academy of Neurology Annual Meeting (AANAM) 2023.

News: April 27, 2023

The Relationship Between Olfactory Dysfunction and Constipation in Early Parkinson's Disease

Publication: Journal Article

Baumgartner, Alexander J, Daniel Z. Press, and David K. Simon MD. 2021. “The Relationship Between Olfactory Dysfunction and Constipation in Early Parkinson’s Disease”. Movement Disorders.

Do somatic mitochondrial DNA mutations contribute to Parkinson's disease?

Publication: Journal Article

Clark, J, Y Dai, and DK Simon. 2010. “Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson’s Disease?”. Parkinson’s Disease.

VPS35-based approach: A potential innovative treatment in Parkinson's disease

Publication: Journal Article

Eleuteri, S, and A Albanese. 2019. “VPS35-Based Approach: A Potential Innovative Treatment in Parkinson’s Disease”. Frontiers in Neurology.

Autonomic and electrocardiographic findings in Parkinson's disease

Publication: Journal Article

Gibbons, CH, DK Simon, M Huang, B Tilley, MJ Aminoff, JL Bainbridge, M Brodsky, et al. 2017. “Autonomic and Electrocardiographic Findings in Parkinson’s Disease”. Autonomic Neuroscience.

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Blog: May 16, 2023

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