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Sphingolipid and Phospholipid Levels Are Altered in Human Brain in Chorea-Acanthocytosis

Publication: Journal Article

Ditzel, RM, RH Walker, MJ Nirenberg, AM Tetlow, K Farrell, KJ Lind-Watson, EL Thorn, et al. 2023. “Sphingolipid and Phospholipid Levels Are Altered in Human Brain in Chorea-Acanthocytosis”. Movement Disorders.

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Pgc-1α overexpression downregulates pitx3 and increases susceptibility to MPTP toxicity associated with decreased bdnf

Publication: Journal Article

Clark, J, JM Silvaggi, T Kiselak, K Zheng, E Clore, Y Dai, CE Bass, and DK Simon. 2012. “Pgc-1α Overexpression Downregulates Pitx3 and Increases Susceptibility to MPTP Toxicity Associated With Decreased Bdnf”. PLoS ONE.

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Blog: May 16, 2023

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Press release in BIDMC News

News: November 14, 2023

"Researchers Halt Progression in Parkinson's Disease Mouse Model" discussed in BIDMC press release Jacqueline Mitchell reports on the Simon Lab's contributions to a deeper understanding of the mechanisms underlying Parkinson's Disease and the best novel targets to investigate potential treatments...

Postdoctoral fellow Dr. Michele Persico (currently at Emory University) presented our work on VPS35 at the American Academy of Neurology Annual Meeting (AANAM) 2023.

News: April 27, 2023

The Relationship Between Olfactory Dysfunction and Constipation in Early Parkinson's Disease

Publication: Journal Article

Baumgartner, Alexander J, Daniel Z. Press, and David K. Simon MD. 2021. “The Relationship Between Olfactory Dysfunction and Constipation in Early Parkinson’s Disease”. Movement Disorders.

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August 11, 2020 Turpis cursus in hac habitasse platea dictumst quisque sagittis purus. Semper feugiat nibh sed pulvinar proin gravida hendrerit lectus. Optio vel quisquam nobis molestiae iste. Quia inventore est libero amet ea explicabo. Assumenda eligendi repudiandae autem omnis pariatur quam omnis...