MiRNA-Binding Site Polymorphisms, Cancer Risk and Outcome
Since miRNAs bind to imperfect complementary sequences in the 3’UTR of target mRNAs to repress target gene expression [3, 4] [1, 2, 5-9], the 3’UTR has rightly received increased interest recently. A new insight into cancer biology has come with the finding that functional single nucleotide...