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Reproducibility in computational sleep research: a call for action.

Publication: Journal Article

Cassidy, Michael J, Danielle A Wallace, Shaun Purcell, and Tamar Sofer. 2024. “Reproducibility in Computational Sleep Research: A Call for Action.”. Sleep 47 (1).

Light exposure during sleep is bidirectionally associated with irregular sleep timing: The multi-ethnic study of atherosclerosis (MESA).

Publication: Journal Article

Wallace, Danielle A, Xinye Qiu, Joel Schwartz, Tianyi Huang, Frank A J L Scheer, Susan Redline, and Tamar Sofer. 2024. “Light Exposure During Sleep Is Bidirectionally Associated With Irregular Sleep Timing: The Multi-Ethnic Study of Atherosclerosis (MESA).”. Environmental Pollution (Barking, Essex : 1987) 344: 123258.

Dr. Xiaonan Liu is from China and currently a G2 PhD student in Biostatistics at Harvard. Her research interests include combining deep learning and traditional statistics to study the pathway from genotype to phenotype, which could aid identifying drug target. Outside of work, she loves dancing and...

Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.

Publication: Journal Article

Li, Josephine H, Laura N Brenner, Varinderpal Kaur, Katherine Figueroa, Philip Schroeder, Alicia Huerta-Chagoya, MAGIC Investigators, et al. 2023. “Genome-Wide Association Analysis Identifies Ancestry-Specific Genetic Variation Associated With Acute Response to Metformin and Glipizide in SUGAR-MGH.”. Diabetologia 66 (7): 1260-72.

Clonal haematopoiesis and risk of chronic liver disease.

Publication: Journal Article

Wong, Waihay J, Connor Emdin, Alexander G Bick, Seyedeh M Zekavat, Abhishek Niroula, James P Pirruccello, Laura Dichtel, et al. 2023. “Clonal Haematopoiesis and Risk of Chronic Liver Disease.”. Nature 616 (7958): 747-54.

Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.

Publication: Journal Article

Hu, Xiaowei, Dandi Qiao, Wonji Kim, Matthew Moll, Pallavi P Balte, Leslie A Lange, Traci M Bartz, et al. 2022. “Polygenic Transcriptome Risk Scores for COPD and Lung Function Improve Cross-Ethnic Portability of Prediction in the NHLBI TOPMed Program.”. American Journal of Human Genetics 109 (5): 857-70.

Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores.

Publication: Journal Article

Hrytsenko, Yana, Benjamin Shea, Michael Elgart, Nuzulul Kurniansyah, Genevieve Lyons, Alanna C Morrison, April P Carson, et al. 2023. “Machine Learning Models for Blood Pressure Phenotypes Combining Multiple Polygenic Risk Scores.”. MedRxiv : The Preprint Server for Health Sciences.

Anaerobic pathogens associated with OSA may contribute to pathophysiology via amino-acid depletion.

Publication: Journal Article

Elgart, Michael, Ying Zhang, Yuan Zhang, Bing Yu, Youngmee Kim, Phyllis C Zee, Marc D Gellman, et al. 2023. “Anaerobic Pathogens Associated With OSA May Contribute to Pathophysiology via Amino-Acid Depletion.”. EBioMedicine 98: 104891.

Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma.

Publication: Journal Article

Recto, Kathryn, Priyadarshini Kachroo, Tianxiao Huan, David Van Den Berg, Gha Young Lee, Helena Bui, Dong Heon Lee, et al. 2023. “Epigenome-Wide DNA Methylation Association Study of Circulating IgE Levels Identifies Novel Targets for Asthma.”. EBioMedicine 95: 104758.