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123 results found

Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.

Publication: Journal Article

Wang, Heming, Nuzulul Kurniansyah, Brian E Cade, Matthew O Goodman, Han Chen, Daniel J Gottlieb, Sina A Gharib, et al. 2022. “Upregulated Heme Biosynthesis Increases Obstructive Sleep Apnea Severity: A Pathway-Based Mendelian Randomization Study.”. Scientific Reports 12 (1): 1472.

Recommendations on the use and reporting of race, ethnicity, and ancestry in genetic research: Experiences from the NHLBI TOPMed program.

Publication: Journal Article

Khan, Alyna T, Stephanie M Gogarten, Caitlin P McHugh, Adrienne M Stilp, Tamar Sofer, Michael L Bowers, Quenna Wong, et al. 2022. “Recommendations on the Use and Reporting of Race, Ethnicity, and Ancestry in Genetic Research: Experiences from the NHLBI TOPMed Program.”. Cell Genomics 2 (8).

Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations.

Publication: Journal Article

Elgart, Michael, Genevieve Lyons, Santiago Romero-Brufau, Nuzulul Kurniansyah, Jennifer A Brody, Xiuqing Guo, Henry J Lin, et al. 2022. “Non-Linear Machine Learning Models Incorporating SNPs and PRS Improve Polygenic Prediction in Diverse Human Populations.”. Communications Biology 5 (1): 856.

Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition.

Publication: Journal Article

Granot-Hershkovitz, Einat, Shan He, Jan Bressler, Bing Yu, Wassim Tarraf, Casey M Rebholz, Jianwen Cai, et al. 2023. “Plasma Metabolites Associated With Cognitive Function across Race/Ethnicities Affirming the Importance of Healthy Nutrition.”. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association 19 (4): 1331-42.

Polygenic risk scores and kidney traits in the Hispanic/Latino population: The Hispanic Community Health Study/Study of Latinos.

Publication: Journal Article

Zhou, Laura Y, Tamar Sofer, Andrea R R Horimoto V, Gregory A Talavera, James P Lash, Jianwen Cai, and Nora Franceschini. 2023. “Polygenic Risk Scores and Kidney Traits in the Hispanic/Latino Population: The Hispanic Community Health Study/Study of Latinos.”. HGG Advances 4 (2): 100177.

Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex.

Publication: Journal Article

Sofer, Tamar, Nuzulul Kurniansyah, Michael Murray, Yuk-Lam Ho, Erik Abner, Tõnu Esko, Estonian Biobank Research Team, et al. 2023. “Genome-Wide Association Study of Obstructive Sleep Apnoea in the Million Veteran Program Uncovers Genetic Heterogeneity by Sex.”. EBioMedicine 90: 104536.

Jack Cummins

Person: Research Student

Jack attends Manchester-Essex Regional High School (MERHS) and loves to apply coding and machine learning tools to medically relevant questions. Jack helped to develop the Python course currently taught at his high school. At MERHS, he is class president, captain of the tennis team, and founder of...

Genevieve Lyons

Person: Master's Student Intern

Genevieve is an Associate Director, Health Economics and Outcomes Research, at Alexion, AstraZeneca Rare Disease Unit. She leads strategy, evidence generation, and outcomes research for pediatric rare diseases. Genevieve graduated with an MS in Health Data Science from Harvard TH Chan School for...

Brian Spitzer

Person: Bioinformatician

Brian is a bioinformatician in Dr. Tamar Sofer's lab. He holds a Ph.D. in Population Biology from the University of California, Davis, and an M.S. in Bioinformatics from Boston University. In his spare time, Brian enjoys cooking Indian food and learning strange things about invertebrates.

A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations.

Publication: Journal Article

Nagarajan, Pavithra, Thomas W Winkler, Amy R Bentley, Clint L Miller, Aldi T Kraja, Karen Schwander, Songmi Lee, et al. 2024. “A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations.”. MedRxiv : The Preprint Server for Health Sciences.