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Prashanth Thevkar Nagesh, PhD
Prashanth is studying immunophenotyping of PBMCs from alcoholic hepatitis patients and their functional profiling in response to PAMPs.
Gyongyi Szabo
Add blurb here https://connects.catalyst.harvard.edu/Profiles/display/Person/28770
Gut and Alcohol
Coming soon
Yeshaswini Katkoori
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Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice.
Ambade, Aditya, Patrick Lowe, Karen Kodys, Donna Catalano, Benedek Gyongyosi, Yeonhee Cho, Arvin Iracheta-Vellve, et al. 2019. “Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice.”. Hepatology (Baltimore, Md.) 69 (3): 1105-21.
Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients.
Fasullo, Matthew, Prashanth Rau, Dong-Qi Liu, Erik Holzwanger, Jomol P Mathew, Yurima Guilarte-Walker, and Gyongyi Szabo. 2019. “Proton Pump Inhibitors Increase the Severity of Hepatic Encephalopathy in Cirrhotic Patients.”. World Journal of Hepatology 11 (6): 522-30.
Inhibition of the Inflammasome Signaling Cascade Reduces Alcohol Consumption in Female But Not Male Mice.
Lowe, Patrick P, Yeonhee Cho, David Tornai, Sahin Coban, Donna Catalano, and Gyongyi Szabo. 2020. “Inhibition of the Inflammasome Signaling Cascade Reduces Alcohol Consumption in Female But Not Male Mice.”. Alcoholism, Clinical and Experimental Research 44 (2): 567-78.
Deficiency of miR-208a Exacerbates CCl4-Induced Acute Liver Injury in Mice by Activating Cell Death Pathways.
Bala, Shashi, Charles D Calenda, Donna Catalano, Mrigya Babuta, Karen Kodys, Imad A Nasser, Barbara Vidal, and Gyongyi Szabo. 2020. “Deficiency of MiR-208a Exacerbates CCl4-Induced Acute Liver Injury in Mice by Activating Cell Death Pathways.”. Hepatology Communications 4 (10): 1487-1501.
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
Lowe, Patrick P, Caroline Morel, Aditya Ambade, Arvin Iracheta-Vellve, Erica Kwiatkowski, Abhishek Satishchandran, Istvan Furi, et al. 2020. “Chronic Alcohol-Induced Neuroinflammation Involves CCR2/5-Dependent Peripheral Macrophage Infiltration and Microglia Alterations.”. Journal of Neuroinflammation 17 (1): 296.