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At the Center for Drug Discovery and Translational Research, BIDMC, Harvard Medical School, Sun Lab offers a platform and expertise in medicinal chemistry to facilitate the translation of research from bench to bedside.
Our laboratory has studied the optimal integration of molecular simulations into the generation of bioactive molecules. In collaboration with investigators at Harvard Medical School, we have applied this research methodology to discover novel immune modulators for the treatment of autoimmune diseases (e.g., Inflammatory Bowel Diseases, Diabetes, etc) and cancers (e.g., Breast cancer). Currently, our interest focuses on Aryl Hydrocarbon Receptor (AHR) modulators, Orai channel blockers, and threonine/serine kinases.

Chemical Biology, Biochemistry, Beth Israel

Immunology Technologies Core at BIDMC, flow cytometric, histotechnology and spatial-omics data generation services

The Functional Genomics and Bioinformatics Core (FunGen Core) at BIDMC provides investigators with end-to-end support for transcriptomic and multiomic studies—from experimental design to data interpretation.

Glycomics Core at BIDMC, Glycomics Core, Glycan Microarrays, Glycan analysis by Mass Spectrometry, Distribution of specific reagents

Spatial Technology Unit (STU), BIDMC Spatial Technology Unit, tissue processing to data analysis, spatial and single cell technologies