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Leo Otterbein, PhD

Person: Professor of Surgery, Harvard Medical School, Director, Translational/Basic Research Career

Dr. Otterbein is Professor of Surgery at Harvard Medical School and joined BIDMC in 2004. He earned his PhD in Physiology at Johns Hopkins University with graduate and postdoctoral training at Yale University and the University of Pittsburgh Medical Center. His research program investigates...

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Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.

Publication: Journal Article

Tahir, Usman A, Daniel H Katz, Julian Avila-Pachecho, Alexander G Bick, Akhil Pampana, Jeremy M Robbins, Zhi Yu, et al. 2022. “Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.”. Nature Communications 13 (1): 4923.

Lp(a) in the Cath Lab: Opportunities for Refined Secondary…and Primary…Prevention of PAD?

Publication: Journal Article

Benson, Mark D. 2022. “Lp(a) in the Cath Lab: Opportunities for Refined Secondary…and Primary…Prevention of PAD?”. JACC. Cardiovascular Interventions 15 (14): 1477-79.

Population health management of low-density lipoprotein cholesterol via a remote, algorithmic, navigator-executed program.

Publication: Journal Article

Plutzky, Jorge, Mark D Benson, Kira Chaney, Tiffany Bui V, Michael Kraft, Lina Matta, Marian McPartlin, et al. 2022. “Population Health Management of Low-Density Lipoprotein Cholesterol via a Remote, Algorithmic, Navigator-Executed Program.”. American Heart Journal 243: 15-27.

Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults.

Publication: Journal Article

Katz, Daniel H, Usman A Tahir, Debby Ngo, Mark D Benson, Yan Gao, Xu Shi, Matthew Nayor, et al. 2021. “Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults.”. Circulation. Genomic and Precision Medicine 14 (3): e003191.

Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk.

Publication: Journal Article

Ngo, Debby, Mark D Benson, Jonathan Z Long, Zsu-Zsu Chen, Ruiqi Wang, Anjali K Nath, Michelle J Keyes, et al. 2021. “Proteomic Profiling Reveals Biomarkers and Pathways in Type 2 Diabetes Risk.”. JCI Insight 6 (5).

Emerging Affinity Reagents for High Throughput Proteomics: Trust, but Verify.

Publication: Journal Article

Benson, Mark D, Debby Ngo, Peter Ganz, and Robert E Gerszten. 2019. “Emerging Affinity Reagents for High Throughput Proteomics: Trust, But Verify.”. Circulation 140 (20): 1610-12.