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Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer.

Publication: Journal Article

Ali, Azhar, Elena Levantini, Jun Ting Teo, Julian Goggi, John G Clohessy, Chan Shuo Wu, Leilei Chen, et al. 2018. “Fatty Acid Synthase Mediates EGFR Palmitoylation in EGFR Mutated Non-Small Cell Lung Cancer.”. EMBO Molecular Medicine 10 (3).

Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms.

Publication: Journal Article

Bezzi, Marco, Nina Seitzer, Tomoki Ishikawa, Markus Reschke, Ming Chen, Guocan Wang, Caitlin Mitchell, et al. 2018. “Diverse Genetic-Driven Immune Landscapes Dictate Tumor Progression through Distinct Mechanisms.”. Nature Medicine 24 (2): 165-75.

mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.

Publication: Journal Article

Matsumoto, Akinobu, Alessandra Pasut, Masaki Matsumoto, Riu Yamashita, Jacqueline Fung, Emanuele Monteleone, Alan Saghatelian, Keiichi I Nakayama, John G Clohessy, and Pier Paolo Pandolfi. 2017. “MTORC1 and Muscle Regeneration Are Regulated by the LINC00961-Encoded SPAR Polypeptide.”. Nature 541 (7636): 228-32.

In Vivo Protocol Design and Implementation

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Agents alone or in combination will be evaluated in vivo in human tumor xenografts in mice, as well as in GEMs obtained by outsourcing or in-house acquisition when requested. We will evaluate each drug or combination of drugs by different routes or different schedules of administration following...

Of model pets and cancer models: an introduction to mouse models of cancer.

Publication: Journal Article

Lunardi, Andrea, Caterina Nardella, John G Clohessy, and Pier Paolo Pandolfi. 2014. “Of Model Pets and Cancer Models: An Introduction to Mouse Models of Cancer.”. Cold Spring Harbor Protocols 2014 (1): 17-31.

Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.

Publication: Journal Article

Nardella, Caterina, Andrea Lunardi, Giuseppe Fedele, John G Clohessy, Andrea Alimonti, Sara C Kozma, George Thomas, Massimo Loda, and Pier Paolo Pandolfi. 2011. “Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant MTORC1 Signaling and Tumorigenesis.”. Cancer Research 71 (10): 3669-75.

beta-tting on p63 as a metastatic suppressor.

Publication: Journal Article

Clohessy, John G, and Pier Paolo Pandolfi. 2009. “Beta-Tting on P63 As a Metastatic Suppressor.”. Cell 137 (1): 28-30.

Differential requirement of mTOR in postmitotic tissues and tumorigenesis.

Publication: Journal Article

Nardella, Caterina, Arkaitz Carracedo, Andrea Alimonti, Robin M Hobbs, John G Clohessy, Zhenbang Chen, Ainara Egia, et al. 2009. “Differential Requirement of MTOR in Postmitotic Tissues and Tumorigenesis.”. Science Signaling 2 (55): ra2.

Specific FAHFAs Predict Worsening Glucose Tolerance in Non-Diabetic Relatives of People with Type 2 Diabetes.

Publication: Journal Article

Syed, Ismail, Ken Sluis, Pratik Aryal, Zachary Solomon, Rucha Patel, Srihari Konduri, Dionicio Siegel, Ulf Smith, and Barbara B Kahn. 2025. “Specific FAHFAs Predict Worsening Glucose Tolerance in Non-Diabetic Relatives of People With Type 2 Diabetes.”. Journal of Lipid Research, 100819.

Depressive Symptoms Among US Adults

Publication: Journal Article

Inoue, Kosuke, Michael Liu, Katherine A Koh, Rahul Aggarwal, Lucas X Marinacci, and Rishi K Wadhera. 2025. “Depressive Symptoms Among US Adults”. JAMA Internal Medicine.