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Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.

Publication: Journal Article

Patnaik, Akash, Kenneth D Swanson, Eva Csizmadia, Aniruddh Solanki, Natalie Landon-Brace, Marina P Gehring, Katja Helenius, et al. 2017. “Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.”. Cancer Discovery 7 (7): 750-65.

Nanoformulation of Olaparib Amplifies PARP Inhibition and Sensitizes PTEN/TP53-Deficient Prostate Cancer to Radiation.

Publication: Journal Article

van de Ven, Anne L, Shifalika Tangutoori, Paige Baldwin, Ju Qiao, Codi Gharagouzloo, Nina Seitzer, John G Clohessy, et al. 2017. “Nanoformulation of Olaparib Amplifies PARP Inhibition and Sensitizes PTEN/TP53-Deficient Prostate Cancer to Radiation.”. Molecular Cancer Therapeutics 16 (7): 1279-89.

SPAR, a lncRNA encoded mTORC1 inhibitor.

Publication: Journal Article

Matsumoto, Akinobu, John G Clohessy, and Pier Paolo Pandolfi. 2017. “SPAR, a LncRNA Encoded MTORC1 Inhibitor.”. Cell Cycle (Georgetown, Tex.) 16 (9): 815-16.

The pleiotropic role of non-coding genes in development and cancer.

Publication: Journal Article

Pasut, Alessandra, Akinobu Matsumoto, John G Clohessy, and Pier Paolo Pandolfi. 2016. “The Pleiotropic Role of Non-Coding Genes in Development and Cancer.”. Current Opinion in Cell Biology 43: 104-13.

NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.

Publication: Journal Article

Rau, Rachel, Daniel Magoon, Sarah Greenblatt, Li Li, Colleen Annesley, Amy S Duffield, David Huso, et al. 2014. “NPMc+ Cooperates With Flt3/ITD Mutations to Cause Acute Leukemia Recapitulating Human Disease.”. Experimental Hematology 42 (2): 101-13.e5.

The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells.

Publication: Journal Article

Fagoonee, Sharmila, Claudia Bearzi, Ferdinando Di Cunto, John G Clohessy, Roberto Rizzi, Markus Reschke, Emanuela Tolosano, et al. 2013. “The RNA Binding Protein ESRP1 Fine-Tunes the Expression of Pluripotency-Related Factors in Mouse Embryonic Stem Cells.”. PloS One 8 (8): e72300.

Subtle variations in Pten dose determine cancer susceptibility.

Publication: Journal Article

Alimonti, Andrea, Arkaitz Carracedo, John G Clohessy, Lloyd C Trotman, Caterina Nardella, Ainara Egia, Leonardo Salmena, et al. 2010. “Subtle Variations in Pten Dose Determine Cancer Susceptibility.”. Nature Genetics 42 (5): 454-8.

Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer.

Publication: Journal Article

Montanaro, L, M Brigotti, J Clohessy, S Barbieri, C Ceccarelli, D Santini, M Taffurelli, et al. 2006. “Dyskerin Expression Influences the Level of Ribosomal RNA Pseudo-Uridylation and Telomerase RNA Component in Human Breast Cancer.”. The Journal of Pathology 210 (1): 10-8.

Delivery Unit from Precision RNA Medicine Core Powers New RNA-Based Cancer Therapy

News: May 05, 2025

In a recent Nature Communications study, Dr. Annalisa Di Ruscio and team introduced aptaDiR, a novel RNA therapeutic engineered to silence DNMT1 and reverse abnormal DNA methylation in cancer. Delivered via lipid nanoparticles, aptaDiR reactivated tumor-suppressor genes and significantly reduced...

Dresser C, Storr L, Leaning J. Disasters and Emergency Planning. In: International Encyclopedia of Public Health (Third Edition), Editor(s): Stella R. Quah. Pages 759-772.

Publication: Journal Article

“Dresser C, Storr L, Leaning J. Disasters and Emergency Planning. In: International Encyclopedia of Public Health (Third Edition), Editor(s): Stella R. Quah. Pages 759-772.”. 2025. International Encyclopedia of Public Health (Third Edition), Editor(s): Stella R. Qua.