Leptin therapy for type 1 diabetes gains traction
Myers, Martin, Ronald Kahn, and Domenico Accili. 2010. “Leptin Therapy for Type 1 Diabetes Gains Traction”. Nat Med 16 (4): 380.
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Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma
Ueda, Shuji, Sohei Kitazawa, Kota Ishida, Yuki Nishikawa, Megumi Matsui, Hikaru Matsumoto, Takuji Aoki, et al. 2010. “Crucial Role of the Small GTPase Rac1 in Insulin-Stimulated Translocation of Glucose Transporter 4 to the Mouse Skeletal Muscle Sarcolemma”. FASEB J 24 (7): 2254-61.
Adipose depots possess unique developmental gene signatures
Yamamoto, Yuji, Stephane Gesta, Kevin Lee, Thien Tran, Parshin Saadatirad, and Ronald Kahn. 2010. “Adipose Depots Possess Unique Developmental Gene Signatures”. Obesity (Silver Spring) 18 (5): 872-78.
Health care reform--need for lessemotion and more science
Kahn, Ronald. 2009. “Health Care Reform--Need for Lessemotion and More Science”. J Clin Invest 119 (10): 2856-7.
Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform
Escribano, Oscar, Carlos Guillén, Carmen Nevado, Almudena Gómez-Hernández, Ronald Kahn, and Manuel Benito. 2009. “Beta-Cell Hyperplasia Induced by Hepatic Insulin Resistance: Role of a Liver-Pancreas Endocrine Axis through Insulin Receptor A Isoform”. Diabetes 58 (4): 820-8.
Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism
Macotela, Yazmin, Jeremie Boucher, Thien Tran, and Ronald Kahn. 2009. “Sex and Depot Differences in Adipocyte Insulin Sensitivity and Glucose Metabolism”. Diabetes 58 (4): 803-12.
Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death
Princen, Frederic, Emilie Bard, Farah Sheikh, Sharon Zhang, Jing Wang, Wagner Zago, Dongmei Wu, et al. 2009. “Deletion of Shp2 Tyrosine Phosphatase in Muscle Leads to Dilated Cardiomyopathy, Insulin Resistance, and Premature Death”. Mol Cell Biol 29 (2): 378-88.
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
Jing, Enxuan, Stephane Gesta, and Ronald Kahn. 2007. “SIRT2 Regulates Adipocyte Differentiation through FoxO1 Acetylation/Deacetylation”. Cell Metab 6 (2): 105-14.
Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes
Farese, Robert, Mini Sajan, Hong Yang, Pengfei Li, Steven Mastorides, William Gower, Sonali Nimal, et al. 2007. “Muscle-Specific Knockout of PKC-Lambda Impairs Glucose Transport and Induces Metabolic and Diabetic Syndromes”. J Clin Invest 117 (8): 2289-301.
Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation
Mouche, Sarah, Sanae Ben Mkaddem, Wei Wang, Masa Katic, Yu-Hua Tseng, Stephanie Carnesecchi, Klaus Steger, et al. 2007. “Reduced Expression of the NADPH Oxidase NOX4 Is a Hallmark of Adipocyte Differentiation”. Biochim Biophys Acta 1773 (7): 1015-27.