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Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans

Publication: Journal Article

Hebinck, Hardt, Schöls, Vorgerd, Briedigkeit, Kahn, and Ristow. 2000. “Heterozygous Expansion of the GAA Tract of the X25/Frataxin Gene Is Associated With Insulin Resistance in Humans”. Diabetes 49 (9): 1604-7.

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

Publication: Journal Article

Michael, Kulkarni, Postic, Previs, Shulman, Magnuson, and Kahn. 2000. “Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction”. Mol Cell 6 (1): 87-97.

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice

Publication: Journal Article

Wojtaszewski, Higaki, Hirshman, Michael, Dufresne, Kahn, and Goodyear. 1999. “Exercise Modulates Postreceptor Insulin Signaling and Glucose Transport in Muscle-Specific Insulin Receptor Knockout Mice”. J Clin Invest 104 (9): 1257-64.

Role of the transmembrane domain and flanking amino acids in internalization and down-regulation of the insulin receptor

Publication: Journal Article

Yamada, Carpentier, Cheatham, Goncalves, Shoelson, and Kahn. 1995. “Role of the Transmembrane Domain and Flanking Amino Acids in Internalization and Down-Regulation of the Insulin Receptor”. J Biol Chem 270 (7): 3115-22.

Picking a research problem. The critical decision

Publication: Journal Article

Kahn. 1994. “Picking a Research Problem. The Critical Decision”. N Engl J Med 330 (21): 1530-3.

The level of insulin receptor tyrosine kinase activity modulates the activities of phosphatidylinositol 3-kinase, microtubule-associated protein, and S6 kinases

Publication: Journal Article

Wilden, and Kahn. 1994. “The Level of Insulin Receptor Tyrosine Kinase Activity Modulates the Activities of Phosphatidylinositol 3-Kinase, Microtubule-Associated Protein, and S6 Kinases”. Mol Endocrinol 8 (5): 558-67.

Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin, and dexamethasone

Publication: Journal Article

Saad, Folli, Araki, Hashimoto, Csermely, and Kahn. 1994. “Regulation of Insulin Receptor, Insulin Receptor Substrate-1 and Phosphatidylinositol 3-Kinase in 3T3-F442A Adipocytes. Effects of Differentiation, Insulin, and Dexamethasone”. Mol Endocrinol 8 (5): 545-57.

The insulin signaling system

Publication: Journal Article

White, and Kahn. 1994. “The Insulin Signaling System”. J Biol Chem 269 (1): 1-4.

Human corneal epithelial primary cultures and cell lines with extended life span: in vitro model for ocular studies

Publication: Journal Article

Kahn, Young, Lee, and Rhim. 1993. “Human Corneal Epithelial Primary Cultures and Cell Lines With Extended Life Span: In Vitro Model for Ocular Studies”. Invest Ophthalmol Vis Sci 34 (12): 3429-41.

Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

Publication: Journal Article

Saad, Folli, Kahn, and Kahn. 1993. “Modulation of Insulin Receptor, Insulin Receptor Substrate-1, and Phosphatidylinositol 3-Kinase in Liver and Muscle of Dexamethasone-Treated Rats”. J Clin Invest 92 (4): 2065-72.