Micro-RNAs: small is plentiful.
Grosshans, Helge, and Frank J Slack. 2002. “Micro-RNAs: Small Is Plentiful.”. The Journal of Cell Biology 156 (1): 17-21.
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Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models.
Struth, Eric, Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn Cramer, Joanna B Dahl, Frank J Slack, Kourosh Zarringhalam, and Jonathan P Celli. 2024. “Drug Resistant Pancreatic Cancer Cells Exhibit Altered Biophysical Interactions With Stromal Fibroblasts in Imaging Studies of 3D Co-Culture Models.”. Scientific Reports 14 (1): 20698.
MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state.
Zhang, Wen Cai, Nicholas Skiados, Fareesa Aftab, Cerena Moreno, Luis Silva, Paul Joshua Anthony Corbilla, John M Asara, Aaron N Hata, and Frank J Slack. 2022. “MicroRNA-21 Guide and Passenger Strand Regulation of Adenylosuccinate Lyase-Mediated Purine Metabolism Promotes Transition to an EGFR-TKI-Tolerant Persister State.”. Cancer Gene Therapy 29 (12): 1878-94.
Photodynamic Stromal Depletion Enhances Therapeutic Nanoparticle Delivery in 3D Pancreatic Ductal Adenocarcinoma Tumor Models.
Karimnia, Vida, Elizabeth Stanley, Christian T Fitzgerald, Imran Rizvi, Frank J Slack, and Jonathan P Celli. 2023. “Photodynamic Stromal Depletion Enhances Therapeutic Nanoparticle Delivery in 3D Pancreatic Ductal Adenocarcinoma Tumor Models.”. Photochemistry and Photobiology 99 (1): 120-31.
The Role of LncRNAs in Uveal Melanoma.
Milán-Rois, Paula, Anan Quan, Frank J Slack, and Álvaro Somoza. 2021. “The Role of LncRNAs in Uveal Melanoma.”. Cancers 13 (16).
The SWI/SNF complex regulates the expression of miR-222, a tumor suppressor microRNA in lung adenocarcinoma.
Peinado, Paola, Alvaro Andrades, Jordi Martorell-Marugán, Jeffrey R Haswell, Frank J Slack, Pedro Carmona-Sáez, and Pedro P Medina. 2021. “The SWI/SNF Complex Regulates the Expression of MiR-222, a Tumor Suppressor MicroRNA in Lung Adenocarcinoma.”. Human Molecular Genetics 30 (23): 2263-71.
Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia.
Lee, Jonathan D, Joao A Paulo, Ryan R Posey, Vera Mugoni, Nikki R Kong, Giulia Cheloni, Yu-Ru Lee, et al. 2021. “Dual DNA and Protein Tagging of Open Chromatin Unveils Dynamics of Epigenomic Landscapes in Leukemia.”. Nature Methods 18 (3): 293-302.
sChemNET: a deep learning framework for predicting small molecules targeting microRNA function.
Galeano, Diego, , Jeffrey Haltom, Chaylen Andolino, Aliza Yousey, Victoria Zaksas, Saswati Das, et al. 2024. “SChemNET: a Deep Learning Framework for Predicting Small Molecules Targeting MicroRNA Function.”. Nature Communications 15 (1): 9149.
miR-155 as a novel clinical target for hematological malignancies.
Witten, Lisa, and Frank J Slack. 2020. “MiR-155 As a Novel Clinical Target for Hematological Malignancies.”. Carcinogenesis 41 (1): 2-7.
Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer.
Gilles, Maud-Emmanuelle, Liangliang Hao, Kaelyn Brown, Jihoon Lim, Sangeeta N Bhatia, and Frank J Slack. 2019. “Tumor Penetrating Nanomedicine Targeting Both an OncomiR and an Oncogene in Pancreatic Cancer.”. Oncotarget 10 (51): 5349-58.