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Researchers Resurrect Ancient Viruses in Hopes of Improving Gene Therapy

Boston, MA Researchers at Massachusetts Eye and Ear and Schepens Eye Research Institute have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina. This discovery, published July 30 in Cell Reports, could potentially be used to design...

Boston ECHO Course Approaching!

With the Boston ECHO Course only a week away, we are busy preparing for the weekend long course and excited to meet and welcome everyone who is planning to come!

Genome editing with CRISPR-Cas9 prevents angiogenesis of the retina

Powerful new technology may lead to novel therapies to prevent vision loss, blindness in those with diseases of the retina Boston, Mass. — A research team from the Schepens Eye Research Institute of Massachusetts Eye and Ear has successfully prevented mice from developing angiogenesis of the retina...

Burroughs Wellcome Fund CASI grant

Po-Ru Loh has been awarded a Burroughs Wellcome Fund Career Award at the Scientific Interface for his research applying statistical phasing methods to detect chromosomal abnormalitiies in blood DNA.

Dr. Stefater receives vitreoretinal scholarship

James “Tony” Stefater, MD, PhD, a vitreoretinal fellow at Mass. Eye and Ear, received the 2017 Vitreoretinal Research Scholarship from the Robert Machemer Foundation in the amount of $20,000 over one year. His winning project, “Development of a novel post-operative intraocular retinal tamponade...

New preprint (Loh et al.): Mixed model association for biobank-scale data sets

Biobank-based genome-wide association studies are enabling exciting insights in complex trait genetics, but much uncertainty remains over best practices for optimizing statistical power and computational efficiency in GWAS while controlling confounders. Here, we introduce a much faster version of...