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One of the research interests in our lab is focused on the deep-molecular characterization of a clinically well-defined cohort of patients anchored in genomic data. Alzheimer’s (AD) and Parkinson’s disease (PD) are heterogeneous disorders with identifiable clinical-pathological subtypes based on...

Analyzing surgical technique in diverse open surgical videos with multi-task machine learning Emmett D. Goodman 1,2*, Krishna K. Patel 1,2*, Yilun Zhang 5, William Locke 1,2, Chris J. Kennedy 5,6, Rohan Mehrotra 1,2, Stephen Ren 1,2, Melody Guan 1,2, Orr Zohar 2,3, Maren Downing 5, Hao Wei Chen 5...

In our laboratory, we use musculoskeletal biomechanics to understand the effects of aging, disease, and personal characteristics on physical function and risk of injury. We are particularly focused on the biomechanics of the human thoracolumbar spine, and seek to evaluate and understand the motion...

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Environmental stress profoundly affects cellular plasticity and metabolism in multicellular organisms. Adipose tissues serve as a unique model to understand the molecular basis of metabolic adaptation: it comprises a dynamic organ that remodels its cellular size and composition in response to a...