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The VanderHorst lab studies how dysfunction of brainstem circuits causes non-motor and hard to treat motor symptoms in Parkinson’s Disease and non-cognitive symptoms in Alzheimer’s Disease and aging. Examples are problems with walking and balance and abnormal breathing during sleep (as in sleep...

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Our lab uses a variety of techniques to study the function and the structure of neural circuits. In our mouse studies, we study the roles of neuron subtypes that make up these circuits using genetically engineered mouse lines and viral vectors. We then modulate these specific neuron subtypes using...