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Benefits of Membership in the HDDC Inclusion in all HDDC activities All members receive advance notice of HDDC seminars, symposia and special events. Reduced fees for use of Core servicesFull Members, Associate Members and Clinical Associates should discuss subsidies with the core director since...

Core Scientists: David Breault, MD, PhD, Amy O’Connell, MD, PhD Core Technicians: Eric Stas, MS, Wanshu Qi, PhD, Prabhath Mannam Services This service provides in-depth protocols, hands-on training, biologics, and ongoing support for the derivation and culture of gastrointestinal organoids/enteroids...

Culture Services for HDDC Members/Non-members MDCK Cells HDDC Member Non-member MDCK Frozen cryovial $ 7.71 $ 15.71 MDCK (maintain cell line per T75 flask/week) $ 7.71 $ 15.71 T84 Cells HDDC Member Non-member T84 Frozen cryovial $ 24.16 $ 64.16 T84 (maintain cell line per T162 flask/week) $ 24.16 $...

Overview: The Gnotobiotics, Microbiology and Metagenomics core assists investigators evaluating the host microbiota and its role in normal physiology and disease. The core includes a number of resources for groups studying the role of the microbiota in human health and disease, including...

Services: Project management and experimental design Patient consent and sample collection logistics Aerobic and anaerobic culture Microbial identification and analysis Phenotypic analyses include short-chain fatty acid (SCFA) profiles in primary samples or cultured isolates Preparation of materials...

Fees: Core B - Boston Children's Hospital (BCH) Microscope HDDC Member BCH/Non-member Non-BCH/Non-Member Industry Zeiss 880/Fast Airyscan $32/hr* $38/hr* $75/hr $115/hr Zeiss Axiovert $5/hr $20/hr $30/hr $50/hr Nikon TE2000 $56/hr $80/hr $143/hr $182/hr Abberior STEDYCON $32/hr* $38/hr* $51/hr* $85...

The mission of the Center’s CTRP is to support basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. To forge connections and support collaboration between HDDC Clinical Associates and Members To...

Theme 3: Gut Microbiome & Microbial Pathogenesis The HDDC members active in this Affinity group include investigators applying advanced sequencing and informatics to study the commensal gut microbiome and its interaction with the immune system. New and continuing members focused on the commensal...

Jonathan Braun, MD, PhD, Chair Professor and Chair, Department of Pathology and Laboratory Medicine University of California Los Angeles Sean P. Colgan, PhD Professor of Medicine and Immunology University of Colorado School of Medicine Lora Hooper, PhD Professor and Chair Immunology Department...

Welcome to the Harvard Digestive Diseases Center (HDDC) The HDDC is an NIH-funded Center that serves a broad community of scientists conducting basic and translational research relevant to the gastrointestinal tract. The HDDC facilitates multidisciplinary research and collaboration among independent...