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In the 1990s, the 2014 Champalimaud Award Laureates worked in parallel and in collaboration to identify vascular endothelial growth factor (VEGF) as the major trigger for angiogenesis in the eye. In 1993, they showed that the human retina synthesizes VEGF, and subsequently demonstrated that VEGF...

2014 António Champalimaud Laureates: Joan W. Miller, MD, FARVO, Evangelos S. Gragoudas, MD, Patricia A. D’Amore, PhD, MBA, FARVO, Lloyd Paul Aiello, MD, PhD, George L. King, MD, Anthony P. Adamis, MD; and Napoleone Ferrara, MD Dear Colleagues, In September, several Mass. Eye and Ear/Harvard Medical...

Dear Colleagues, Nearly five million people in the world are blind from corneal disease in both eyes, and millions more have corneal blindness in one eye. For some people, conventional corneal transplantation is a successful and life-changing intervention. Many others, however, suffer multiple...

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For many years, the placebo effect was considered to be no more than a nuisance variable that needed to be controlled in clinical trials. Only recently have researchers redefined it as the key to understanding the healing that arises from medical ritual, the context of treatment, the patient...

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