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The most common symptoms of posterior uveitis are blurred vision and floaters, and the most common signs are chorioretinal infiltrates and vitreous cells. Posterior uveitis is diagnosed by slit lamp examination and indirect ophthalmoscopy. Imaging modalities, including fundus autofluorescence...

While gene therapy is not yet widely available for inherited retinal disorsers (IRDs), researchers are making exciting discoveries, and the future looks more promising than ever before. In this issue of eye Insights, we provide a look into current offerings in gene therapy, and a glimpse into the...

Inherited retinal disorders are rare, hereditary disorders caused by mutations in genes that encode proteins needed for normal retinal health and function. The first gene associated with retinitis pigmentosa was identified at Mass Eye and Ear in 1990, and since then, over 250 IRD-causing genes have...

The first gene-augmentation therapy for an IRD was approved by the U.S. Food and Drug Administration (FDA) in December 2017 after nearly two decades of development in preclinical models and clinical trials. The drug, known as Luxturna®, is for individuals with autosomal recessive retinal dystrophies...

Harvard Ophthalmology research contributions have resulted in major advancements in medical science and ophthalmic practice. Discoveries made in various fields—including genetics, immunology and ocular biology—have reshaped the foundations of ophthalmology and formed many new paradigms for the...

Harvard Medical School comprises a network of formal hospital and research affiliations, which provide patient care in addition to medical and research training. Accordingly, Harvard Ophthalmology has evolved into an academic institution with a multi-institutional structure and a broad base of...

Massachusetts General Hospital (MGH) is consistently named one of the top hospitals in the nation and #1 in New England by U.S. News & World Report. Working collaboratively within Harvard’s broad network, the clinicians and researchers in this world-class institution are bringing scientific...

Beth Israel Deaconess Medical Center (BIDMC) is one of the nation's preeminent academic medical centers, committed to providing excellence in clinical care, teaching, research and community outreach. BIDMC is ranked each year as a "Best Hospital" by U.S. News & World Report in multiple specialties...

The VA Boston Healthcare System's consolidated facility consists of: Jamaica Plain campus, located in the heart of Boston's Longwood Medical Area) West Roxbury campus, located on the Dedham line Brockton campus, located 20 miles south of Boston. Visit the Boston VA Healthcare System website