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Message from the Editor-in-Chief

Dear Colleagues, Research in gene augmentation and genome editing for the treatment of inherited retinal disorders (IRDs) is thriving. It is estimated that IRDs affect about 200,000- 300,000 people in the United States and 4-6 million people worldwide. Most patients with these conditions become...

Gene Therapy, Gene Editing, and IRDs

Gene-Augmentation Therapy Gene therapy typically refers to gene-augmentation therapy. In this approach, a healthy version of the mutated gene is packaged inside an engineered and nonpathogenic form of adeno-associated virus (AAV), with the virus serving as a vector to carry the gene. AAV does not...

Gene Therapy for Other Ophthalmic Conditions

Advances in the future may include viral vectors, non-viral vectors, and delivery methods that allow treatment of a greater retinal expanse and an expanded approach to technical challenges related to gene size and disease mechanisms. Genetic therapies for non-retinal ophthalmic diseases are also...

2022 AUPO Annual Meeting

Harvard Ophthalmology was well represented at the Association of University Professors of Ophthalmology (AUPO) annual meeting last month. Chair Joan W. Miller, MD, the President-elect of AUPO, served as Program Committee Chair for the five-day event. Alice Lorch, MD, MPH, Assistant Professor of...

Meredith Gregory-Ksander, PhD, Awarded NIH R01 Grant for Glaucoma Research

The destruction of retinal ganglion cells caused by the type II transmembrane protein Fas ligand (Fasl) is a key factor in glaucoma pathogenesis. Meredith Gregory-Ksander, PhD, Assistant Professor of Ophthalmology and Assistant Scientist at Schepens Eye Research Institute of Mass Eye and Ear, and Co...

Ophthalmology Residents Receive ASCRS Awards

Yanna Bian, MD, a PGY-3 resident, and Sarah Wang, MD, a PGY-4 resident, have been selected as two of the 10 winners of the American Society of Cataract and Refractive Surgery (ASCRS) Foundation 2022 Resident Excellence Award. This award enables ophthalmology residents exhibiting exemplary...

Jonathan R. Soucy, PhD, Receives National Research Service Award from NEI

Jonathan R. Soucy, PhD, a postdoctoral research fellow at Schepens Eye Research Institute of Mass Eye and Ear, is a recipient of the Ruth L. Kirschstein National Research Service Award. This three-year grant from the National Eye Institute will provide $209,046 in funding for his project,...

Boston Magazine Top Doctors 2022

Congratulations to the following Harvard Ophthalmology faculty and alumni who were each recognized as one of "Boston's Top Doctors 2022" by Boston magazine. Beth Israel Deaconess Medical Center Mark C. Kuperwaser, MD Boston Children's Hospital Linda R. Dagi, MD Gena Heidary, MD David G. Hunter, MD...

Harvard Ophthalmology Ranked Among the Best in the Nation

We’re pleased to share that Harvard Ophthalmology/Mass Eye and Ear has once again been ranked among the top departments in the nation by Ophthalmology Times for our excellence in clinical care, research, and education. For the second year in a row, our program was ranked third overall, second in...