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Gene-Augmentation Therapy Gene therapy typically refers to gene-augmentation therapy. In this approach, a healthy version of the mutated gene is packaged inside an engineered and nonpathogenic form of adeno-associated virus (AAV), with the virus serving as a vector to carry the gene. AAV does not...

Advances in the future may include viral vectors, non-viral vectors, and delivery methods that allow treatment of a greater retinal expanse and an expanded approach to technical challenges related to gene size and disease mechanisms. Genetic therapies for non-retinal ophthalmic diseases are also...

Dear Colleagues, In this issue of eye Insights, we take a close look at nonorganic vision loss (NVL). Inside, you’ll find techniques and tips for evaluating and managing patients with NVL. It can be challenging and extremely time consuming to prove that a patient’s visual acuity potential is better...

Patients who are, or may become, limited by their vision loss can benefit from vision rehabilitation. Individuals with acquired or genetic diagnoses that render them mildly, moderately, or severely visually impaired. Even those who are totally blind can benefit from vision rehabilitation. Rachel...

IIH (also known as pseudotumor cerebri) is a disorder of idiopathic raised intracranial pressure primarily affecting overweight women of childbearing age, with an incidence of 3-4 per 100,000. Patients typically present with headaches (90%) that have nonspecific features of migraine or tension-type...

A recent update to the modified Dandy Criteria for IIH is used for diagnosis. Diagnosis relies on accurately identifying papilledema and excluding secondary forms of intracranial hypertension with neuroimaging. A lumbar puncture to ensure normal cerebrospinal fluid (CSF) constituents and confirm an...

In this issue of e ye Insights, we discuss new diagnostic, medical, and surgical innovations that are advancing treatments for glaucoma. We also include guidelines for comprehensive eye exams and links to patient handouts. In this issue: New Tools for Managing Glaucoma: From the Editor-in-Chief...

The Problem Glaucoma is a leading cause of blindness worldwide that is significantly under-diagnosed. The Solution Early detection and monitoring of glaucoma progression is critical to prevent damage to the optic nerve and minimize vision loss. The Way Forward 1. Educate patients about risk factors...

Your patient is a 25-year-old man with myopia. His prescription has been stable for several years. He shows no corneal abnormalities and is generally healthy with no comorbidities. He asks, “Am I a good candidate for LASIK?” Yes. Good candidates are 21 years and older, have good eye and general...

Your patient is a 28-year-old mother of two with stable vision and some irregularities in the shape of her cornea. She wears contacts, but sometimes they irritate her eyes. She has a thin cornea, mild dry eye, and occasionally uses eye drops. She asks, “Am I a good candidate for PRK?” Yes. PRK may...