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Research

Propagation of Light in Turbid Media From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. The theory of radiative transfer is widely used to treat this problem by considering the transport of light energy through a...

Label-Free Nanoscale-Sensitive Study of Sub-Cellular Morphology

Despite the fact that cancer is a disease caused by genetic abnormalities, the most widely accepted means of diagnosing and characterizing cancer cells is with H&E stained microscopic imaging. The identifying features of cancer include abnormally large and crowded cell nuclei with altered cellular...

Exosomes as Extracellular Mediators of Cancer

We gained new insight into the potential for some types of extracellular RNA called microRNA (miRNA) to influence cancer progression ( Cancer Cell 2014 ). The research suggests that cancer cell exosomes, vesicles that are secreted by cells and present in many biological fluids, and the associated...

CABIP

Center for Advanced Biomedical Imaging and Photonics studies the interaction of light with biological tissue on the microscopic and macroscopic scale. Scientists at the Center work at the interface of biophotonics, bioengineering and cancer biology, with a particular emphasis on: scattering of...

Book Chapters

Perelman LT, Modell MD, Vitkin EI and Hanlon EB. Chapter 9. Light Scattering Spectroscopy: From Elastic to Inelastic. In: Tuchin V, editor. Coherent-Domain Optical Methods for Biomedical Diagnostics, Environmental and Material Science. Bristol and Philadelphia: Institute of Physics Publishing; 2004...

Current Funding

R01 CA228029 (PI: Perelman)Spectro-Holographic Instrument for Dynamic Sensing of Cancer ProgressionProject Dates: 2018 - 2023Budget: $3.5M R01 CA205431 (PI: Perelman)Isolation and Assessment of Blood-Circulating Cancer Exosomes with LSS and SERS Lab on a Chip Optical Spectroscopic InstrumentProject...

Test

The Center for Advanced Biomedical Imaging and Photonics studies the interaction of light with biological tissue on the microscopic and macroscopic scale. Scientists at the Center work at the interface of biophotonics, bioengineering and cancer biology, with a particular emphasis on: · scattering of...