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CV
SERS-based Ultrasensitive Identification and Quantification of Drugs in Biofluids
The enormous increase of Raman signal in the vicinity of metal nanoparticles allows surface-enhanced Raman spectroscopy (SERS) to be employed for label-free detection of substances at extremely low concentrations. However, the ultimate potential of label-free SERS to identify pharmaceutical...
Exosomes as Extracellular Mediators of Cancer
We gained new insight into the potential for some types of extracellular RNA called microRNA (miRNA) to influence cancer progression ( Cancer Cell 2014 ). The research suggests that cancer cell exosomes, vesicles that are secreted by cells and present in many biological fluids, and the associated...
The Thermoelastic Basis of Short Pulsed Laser Ablation of Biological Tissue
I, Itzkan, Albagli D, Dark M, Perelman LT, Rosenberg C, and Feld MS. 1995. “The Thermoelastic Basis of Short Pulsed Laser Ablation of Biological Tissue”. Proc. Nat. Acad. Sci. USA 92: 1960-64.
Multispectral Scanning during Endoscopy Guides Biopsy of Dysplasia in Barrett’s Esophagus
L, Qiu, Pleskow D, Chuttani R, Vitkin E, Leyden J, Ozden N, Itani S, et al. 2010. “Multispectral Scanning During Endoscopy Guides Biopsy of Dysplasia in Barrett’s Esophagus”. Nature Medicine 16: 603-6.
Functional Imaging of Epithelial Tissues with Polarized Light Scattering Spectroscopy
R, Gurjar, Backman V, Perelman LT, Georgakoudi I, Badizadegan K, Itzkan I, Dasari RR, and Feld MS. 2001. “Functional Imaging of Epithelial Tissues With Polarized Light Scattering Spectroscopy”. Nature Medicine 7: 1245-48.
Observation of Periodic Fine Structure in Reflectance from Biological Tissue: A New Technique for Measuring Nuclear Size Distribution
LT, Perelman, Backman V, Wallace M, Zonios G, Manoharan R, Nusrat A, Shields S, et al. 1998. “Observation of Periodic Fine Structure in Reflectance from Biological Tissue: A New Technique for Measuring Nuclear Size Distribution”. Phys. Rev. Lett. 80: 627-30.
Imaging and Microscopy Methods in Biology and Medicine
Propagation of Light in Turbid Media
From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. The theory of radiative transfer is widely used to treat this problem by considering the transport of light energy through a random medium and neglecting the wave...