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PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation

Publication: Journal Article

Nath, Anjali, Justine Ryu, Youngnam Jin, Lee Roberts, Andre Dejam, Robert Gerszten, and Randall T. Peterson. 2015. “PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation”. Cell Rep.

Anjali Nath

Person: Principal Investigator , Assistant Professor

Elizabeth Jones

Person: Administrative Assistant

Bio

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Research Focus

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The overarching goals of the lab are to accelerate the identification of novel therapeutic targets for human diseases by leveraging chemical biology tools and multi-omic human datasets.

Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects

Publication: Journal Article

Nath, Anjali, Michael Krauthammer, Puyao Li, Eugene Davidov, Lucas Butler, Joshua Copel, Mikko Katajamaa, et al. 2009. “Proteomic-Based Detection of a Protein Cluster Dysregulated During Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects”. PLoS One 4 (1): e4221.

Leptin is an autocrine/paracrine regulator of wound healing

Publication: Journal Article

Murad, Ali, Anjali Nath, Sung-Tae Cha, Erhan Demir, Jaime Flores-Riveros, and Rocio Sierra-Honigmann. 2003. “Leptin Is an Autocrine/Paracrine Regulator of Wound Healing”. FASEB J 17 (13): 1895-7.

Induction of angiogenesis in a mouse model using engineered transcription factors

Publication: Journal Article

Rebar, Edward, Yan Huang, Reed Hickey, Anjali Nath, David Meoli, Sameer Nath, Bingliang Chen, et al. 2002. “Induction of Angiogenesis in a Mouse Model Using Engineered Transcription Factors”. Nat Med 8 (12): 1427-32.

Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning

Publication: Journal Article

Sips, Patrick, Xu Shi, Gabriel Musso, Anjali Nath, Yanbin Zhao, Jason Nielson, Jordan Morningstar, et al. 2018. “Identification of Specific Metabolic Pathways As Druggable Targets Regulating the Sensitivity to Cyanide Poisoning”. PLoS One 13 (6): e0193889.

Jordan Morningstar (Alumni)

Person: Mass Spectrometrist