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Research

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The Kahn Lab is investigating the mechanism of insulin action and its alterations in insulin resistant states, including type 2 diabetes, obesity and metabolic syndrome. There are 3 major areas of research: 1) Insulin action and insulin resistance. In this area we have projects focusing on the...

Insulin action - Mechanisms of insulin resistance

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Differential signaling by insulin and IGF-1 receptors Differences in downstream signaling (IRS proteins/PI 3-kinase) Signaling by unoccupied insulin receptor Cellular and whole animal analysis using KO and KI mice Signaling in unusual tissues, e.g. the gut and brain

Prof C. Ronald Kahn

Person: Professor at Harvard Medical School
C. Ronald Kahn is a world recognized expert in diabetes and obesity research, as well as a preeminent investigator in the area of insulin signal transduction and mechanisms of altered signaling in diabetes and metabolic disease. Dr. Kahn is Senior Investigator, Head of the Section on Integrative...